Anticancer Potential of Nature-Derived Isoquinoline Alkaloids (A Review)

被引：1
|
作者：
Liu, B. -s. [1 ,2 ]
Liu, K. [1 ,2 ]
Wang, J. [2 ]
Shi, Y. -m. [1 ,2 ]
机构：
[1] Hubei Univ Sci & Technol, Hubei Engn Res Ctr Fragrant Plants, Xianning 437100, Peoples R China
[2] Xianning Res Acad Ind Technol Osmanthus Fragrans, Xianning 437100, Peoples R China
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2023年 / 93卷 / 05期
关键词：
isoquinoline alkaloids; natural products; antiproliferative activity; anticancer potential; CYTOTOXIC ALKALOIDS;
D O I：
10.1134/S1070363223050286
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Isoquinoline alkaloids, vastly found in nature and predominant in Papaveraceae, Berberidaceae, and Ranunculaceae plant families, possess fascinating chemical functionality and unique mechanism diversity. Isoquinoline alkaloids exhibit potent broad-spectrum anticancer activity through various mechanisms, inclusive of arrest cell cycle and induce apoptosis, representing a fertile source for discovery of novel anticancer therapeutic agents. The purpose of the present review article is to provide a comprehensive landscape of nature-derived isoquinoline alkaloids as potential anticancer agents including their mechanisms of action, covering articles published from 2018 to present.
引用
收藏
页码：1294 / 1310
页数：17
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