Unexpected false-negative result in a traveller's malaria diagnosis

被引:0
|
作者
Perez-Ugarte, Arantxa [1 ]
Rubio Maturana, Carles [2 ]
Silgado, Aroa [1 ,3 ]
Zarzuela Serrat, Francesc [1 ]
Goterris, Lidia [1 ]
Paredes-Carmona, Fernando [4 ]
Sulleiro, Elena [1 ,3 ,5 ]
机构
[1] Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Microbiol Dept, PROS Barcelona, Barcelona 08035, Spain
[2] Univ Autonoma Barcelona, Microbiol Dept, Barcelona 08035, Spain
[3] Inst Salud Carlos III, CIBERINFEC, Madrid, Spain
[4] Arnau Vilanova Univ Hosp, Dept Paediat, Lleida 25198, Spain
[5] Hosp Univ Vall dHebron, Serv Microbiol, P Vall dHebron119 129, Barcelona 08035, Spain
关键词
Prozone effect; rapid diagnostic tests; HRP-2; microscopic examination; malaria; TESTS;
D O I
10.1093/jtm/taac124
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
A 4-year-old traveller returned from Senegal with symptoms compatible with malaria. Plasmodium falciparum HRP-2 antigen detection was negative, whereas panmalarial aldolase was positive. Microscopy confirmed the presence of P. falciparum trophozoites with parasitaemia of 16%. Discarding other causes of false-negative antigen detection, this is a rare case of prozone effect.
引用
收藏
页数:2
相关论文
共 50 条
  • [11] False-negative result with the rapid diagnostic test in Plasmodium ovate infection
    Lopez-Feijoo, Carlos
    Sanchez, Isabel
    Damaso, Diego
    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA, 2009, 27 (05): : 306 - 307
  • [12] FALSE-NEGATIVE PRENATAL-DIAGNOSIS OF RESTRICTIVE DERMOPATHY
    HAMEL, BCJ
    HAPPLE, R
    STEYLEN, PM
    KOLLEE, LAA
    STEKHOVEN, JHS
    NIJHUIS, JG
    RAUSKOLB, R
    ANTONLAMPRECHT, I
    AMERICAN JOURNAL OF MEDICAL GENETICS, 1992, 44 (06): : 824 - 826
  • [14] Factors associated with false-negative pathologic diagnosis of calciphylaxis
    Williams, Erik A.
    Moy, Andrea P.
    Cipriani, Nicole A.
    Nigwekar, Sagar U.
    Nazarian, Rosalynn M.
    JOURNAL OF CUTANEOUS PATHOLOGY, 2019, 46 (01) : 16 - 25
  • [15] What is a false-negative result for sentinel node procedures in breast cancer?
    Estourgie, SH
    Nieweg, OE
    Rutgers, EJTH
    Kroon, BBR
    JOURNAL OF SURGICAL ONCOLOGY, 2003, 82 (03) : 141 - 142
  • [16] FALSE-NEGATIVE CPKS
    NIERENBERG, DW
    NEW ENGLAND JOURNAL OF MEDICINE, 1977, 297 (16): : 894 - 894
  • [17] CT PORTOGRAPHY IN THE PRESENCE OF LIVER STEATOSIS - POTENTIAL FOR A FALSE-NEGATIVE RESULT
    STEINER, W
    SCHEIDLER, J
    KOHZ, P
    STABLER, A
    REISER, M
    RADIOLOGE, 1994, 34 (02): : 84 - 87
  • [18] False-negative tests
    Goossens, A
    PROGRESS IN DERMATO-ALLERGOLOGY, 2003, : 149 - 152
  • [19] The False-negative Phenotype
    Lantos, John D.
    PEDIATRICS, 2019, 143 : S33 - S36
  • [20] FALSE-NEGATIVE MARGINS
    HIRSCH, P
    JOURNAL OF DERMATOLOGIC SURGERY AND ONCOLOGY, 1989, 15 (04): : 452 - 453