SYNTHESIS, STRUCTURAL ELUCIDATION AND ANTIBACTERIAL POTENTIAL OF 7,8-DIIMINO PYRAZINO[1,2-A]PYRIMIDO[4,5- D]PYRIMIDO[2,1-B]BENZOTHIAZOLE AND ITS SUBSTITUTED ANALOGS

被引：0

作者：

Kadam, Digambar B. ^{[1
]}

Sontakke, Sandeep G. ^{[2
]}

Pawde, Avinash, V ^{[3
]}

Vartale, Sambhaji P. ^{[4
]}

机构：

[1] Indira Gandhi Sr Coll, Dept Chem, CIDCO, Nanded 431603, Maharashtra, India

[2] SSGG Commerce & SSAM Sci Coll, DBNP Arts, Lonavala 410403, Maharashtra, India

[3] AES Arts Commerce & Sci Coll, Dept Chem, Hingoli 431513, Maharashtra, India

[4] Yeshwant Mahavidyalaya, PG Res Ctr, Dept Chem, Nanded 431602, Maharashtra, India

来源：

HETEROCYCLIC LETTERS | 2023年 / 13卷 / 04期

关键词：

3-cyano-4-imino-2-(methylthio)-4H-pyrimido[1,2-a]pyrazine; 2-amino benzothiazoles; N; N-dimethyl formamide; anhydrous potassium carbonate; antibacterial activity; DERIVATIVES; BROPIRIMINE;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 7,8-diimino pyrazino[1,2-a]pyrimido[4,5-d]pyrimido[2,1-b]benzothiazole and its 2/3/5 substituted derivatives have been reported by condensation of 3-cyano-4-imino-2-(methylthio)-4H-pyrimido[1,2-a]pyrazine with various 2-amino benzothiazole derivatives. To ensure the accuracy of the synthesized compounds' structures, multiple analytical techniques were employed, including Infrared Spectroscopy (IR), Nuclear Magnetic Resonance (NMR), and Mass Spectrometry. Furthermore, the newly synthesized compounds were subjected to an assessment of their antibacterial activity. This evaluation aimed to determine the potential of these compounds in inhibiting bacterial growth, thereby contributing to our understanding of their therapeutic applications.

引用

页码：691 / 696

页数：6

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