SUMO E3 Ligase ZMIZ1 Drives Leukemogenesis Via Transcriptional Deregulation in Acute Myeloid Leukemia

被引：0
|
作者：
Fu Ziyu [1 ]
Tan, Yun [1 ]
Xu, Xiaoguang [1 ]
Xu, Jie [1 ]
Chen, Sai-Juan [1 ]
机构：
[1] Shanghai Jiao Tong Univ SJTU, Natl Res Ctr Translat Med, State Key Lab Med Genom, Shanghai Inst Hematol,Ruijin Hosp,Sch Med, Shanghai, Peoples R China
来源：
BLOOD | 2023年 / 142卷
关键词：
D O I：
10.1182/blood-2023-187978
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：2
相关论文
共 50 条
  • [41] The Activity of Hepatocyte Nuclear Factor-1 Alpha Is Regulated by the E3 SUMO Ligase PIASy
    Aukrust, Ingvild
    Kaci, Alba
    Gundersen, Lise Bjorkhaug
    Njolstad, Pal R.
    DIABETES, 2015, 64 : A737 - A738
  • [42] CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia
    Hansen, Joshua D.
    Correa, Matthew
    Alexander, Matt
    Nagy, Mark
    Huang, Dehua
    Sapienza, John
    Lu, Gang
    LeBrun, Laurie A.
    Cathers, Brian E.
    Zhang, Weihong
    Tang, Yang
    Ammirante, Massimo
    Narla, Rama K.
    Piccotti, Joseph R.
    Pourdehnad, Michael
    Lopez-Girona, Antonia
    JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (04) : 1835 - 1843
  • [43] Mutation in SUMO E3 ligase, SIZ1, Disrupts the Mature Female Gametophyte in Arabidopsis
    Ling, Yu
    Zhang, Chunyu
    Chen, Tong
    Hao, Huaiqing
    Liu, Peng
    Bressan, Ray A.
    Hasegawa, Paul M.
    Jin, Jing Bo
    Lin, Jinxing
    PLOS ONE, 2012, 7 (01):
  • [44] A mechanism for transcriptional repression dependent on the BRCA1 E3 ubiquitin ligase
    Horwitz, Andrew A.
    Affar, El Bachir
    Heine, George F.
    Shi, Yang
    Parvin, Jeffrey D.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (16) : 6614 - 6619
  • [45] The Arabidopsis E3 SUMO ligase SIZ1 regulates plant growth and drought responses
    Catala, Rafael
    Ouyang, Jian
    Abreu, Isabel A.
    Hu, Yuxin
    Seo, Haksoo
    Zhang, Xiuren
    Chua, Nam-Hai
    PLANT CELL, 2007, 19 (09): : 2952 - 2966
  • [46] FLI-1 functionally interacts with PIASxα, a member of the PIAS E3 SUMO ligase family
    van den Akker, E
    Ano, S
    Shih, HM
    Wang, LC
    Pironin, M
    Palvimo, JJ
    Kotaja, N
    Kirsh, O
    Dejean, A
    Ghysdael, J
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (45) : 38035 - 38046
  • [47] Topors acts as a SUMO-1 E3 ligase for p53 in vitro and in vivo
    Weger, S
    Hammer, E
    Heilbronn, R
    FEBS LETTERS, 2005, 579 (22) : 5007 - 5012
  • [48] Targeting GSPT1 by a novel cereblon E3 ligase modulator for the treatment of Acute Lymphoblastic Leukemia
    Keramatnia, Fatemeh
    Chang, Yunchao
    Nishiguchi, Gisele
    Min, Jaeki
    Mullighan, Charles
    Fischer, Marcus
    Rankovic, Zoran
    Keramatnia, Fatemeh
    MOLECULAR CANCER THERAPEUTICS, 2021, 20 (12)
  • [49] Genetic deletion and pharmacologic inhibition of E3 ubiquitin ligase HOIP impairs the propagation of myeloid leukemia
    Jimbo, Koji
    Hattori, Ayuna
    Koide, Shuhei
    Ito, Takahiro
    Sasaki, Katsuhiro
    Iwai, Kazuhiro
    Nannya, Yasuhito
    Iwama, Atsushi
    Tojo, Arinobu
    Konuma, Takaaki
    LEUKEMIA, 2023, 37 (01) : 122 - 133
  • [50] Genetic deletion and pharmacologic inhibition of E3 ubiquitin ligase HOIP impairs the propagation of myeloid leukemia
    Koji Jimbo
    Ayuna Hattori
    Shuhei Koide
    Takahiro Ito
    Katsuhiro Sasaki
    Kazuhiro Iwai
    Yasuhito Nannya
    Atsushi Iwama
    Arinobu Tojo
    Takaaki Konuma
    Leukemia, 2023, 37 : 122 - 133
12345