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Unloading of the Left Ventricle With More Delayed Reperfusion May Reduce Reperfusion Injury
被引:0
|作者:
Hazaveh, Sara
[1
]
Faraz, Haroon
[2
]
机构:
[1] Hackensack Univ, Internal Med, Med Ctr, Hackensack, NJ 07601 USA
[2] Hackensack Univ, Intervent Cardiol, Med Ctr, Hackensack, NJ USA
关键词:
cardiac catherization;
left ventricular unloading;
door to balloon time;
reperfusion injury;
acute st- elevation myocardial infarction;
MYOCARDIAL-INFARCTION;
SIZE;
MORTALITY;
D O I:
10.7759/cureus.52831
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Early reperfusion therapy is crucial and the standard of care for the management of acute ST-elevation myocardial infarction (STEMI). We report a case of STEMI with unloading followed by more delayed reperfusion, which challenges current clinical practice. It also highlights the importance of more translational research to better understand STEMI on a mechanistic level including the crucial role of mitochondria and anaerobic respiration during vessel occlusion and ischemia. This can also help in preventing post-myocardial infarction complications such as reperfusion injury, which leads to the development of heart failure.
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