Synthesis of 2-(Methylthio)-1,3-dithioles from 1,3-Dithiole-2-thiones: Important Building Blocks in Tetrathiafulvalene Chemistry

被引：4

作者：

Granhoj, Jeppe ^{[1
]}

Pedersen, Viktor Bliksted Roug ^{[1
]}

Kroll, Peter Lundgard ^{[1
]}

Brolos, Line ^{[1
]}

Nielsen, Mogens Brondsted ^{[1
]}

机构：

[1] Univ Copenhagen, Dept Chem, DK-2100 Copenhagen, Denmark

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 88卷 / 17期

关键词：

DERIVATIVES; GENERATION; SYSTEMS; DONORS;

D O I：

10.1021/acs.joc.3c01369

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-(Methylthio)-1,3-dithioles are important heterocyclic compounds used for the preparation of redox-active derivatives of tetrathiafulvalene as they serve as precursors for phosphonate esters that can be employed in Horner-Wadsworth Emmons olefination reactions. Here, we present a mild and less hazardous method than previous methods for converting readily accessible 1,3-dithiole-2-thiones into 2-(methylthio)-1,3-dithioles by methylation with trimethyl orthoformate and HBF4.Et2O and a subsequent reduction with NaBH4.

引用

页码：12853 / 12856

页数：4

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