What Causes Seizures in Neurocysticercosis?

被引：7
|
作者：
Steyn, Teresa Julieta Simoes [1 ,2 ]
Awala, Amalia Naita [1 ,2 ]
de Lange, Anja [1 ,2 ]
Raimondo, Joseph Valentino [1 ,2 ,3 ]
机构：
[1] Univ Cape Town, Neurosci Inst, Div Cell Biol, Dept Human Biol, Western Cape, South Africa
[2] Univ Cape Town, Inst Infect Dis & Mol Med, Fac Hlth Sci, Western Cape, South Africa
[3] Univ Cape Town, Fac Hlth Sci, Anat Bldg, ZA-7935 Western Cape, South Africa
来源：
EPILEPSY CURRENTS | 2023年 / 23卷 / 02期
基金：
英国惠康基金;
关键词：
cestode; inflammation; neurocysticercosis; seizures; Taenia solium; BLOOD-BRAIN-BARRIER; TAENIA-SOLIUM CYSTICERCOSIS; PIG FARMING COMMUNITY; CALCIFIED NEUROCYSTICERCOSIS; ANTIPARASITIC TREATMENT; SLICE CULTURES; EPILEPSY; ASSOCIATION; INFECTION; LESIONS;
D O I：
10.1177/15357597221137418
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Neurocysticercosis (NCC) is the most prevalent parasitic infection of the central nervous system. It is caused by the presence of larvae of the cestode Taenia solium in the brain. The most common symptom of NCC is seizures, and it is widely considered the world's leading cause of preventable epilepsy. Despite the prevalence and impact of NCC, a thorough, mechanistic understanding of seizure generation is still lacking. In this review, we address the question "What causes seizures in NCC?" by summarizing and discussing the major theories that seek to explain the seizurogenic and epileptogenic processes in this disorder. In addition, we highlight the potential for recent advances in disease modeling to help accelerate progress in this area.
引用
收藏
页码：105 / 112
页数：8
相关论文
共 50 条
  • [31] What triggers seizures in neurocysticercosis? A MRI-based study in pig farming community from a district of North India
    Prasad, Amit
    Gupta, Rakesh K.
    Pradhan, Sunil
    Tripathi, Mukesh
    Pandey, Chandra M.
    Prasad, Kashi N.
    PARASITOLOGY INTERNATIONAL, 2008, 57 (02) : 166 - 171
  • [32] Seizures! Neurocysticercosis: A Diagnostic Puzzle for the Emergency Physician and the Importance of Imaging
    Bollepalli, S.
    Yost, A.
    Gridley, D.
    Hedayati, P.
    AMERICAN JOURNAL OF ROENTGENOLOGY, 2009, 192 (05)
  • [33] New understanding about the relationship among neurocysticercosis, seizures, and epilepsy
    Carpio, Arturo
    Romo, Matthew L.
    Hauser, W. Allen
    Kelvin, Elizabeth A.
    SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021, 90 : 123 - 129
  • [34] INFLAMMATION IS A KEY RISK FACTOR FOR REFRACTORY SEIZURES IN PATIENTS WITH NEUROCYSTICERCOSIS
    Herrick, Jesica A.
    Garg, Anjali
    Kim, Jin Suh
    Maharathi, Biswajit
    Gomez Abundis, Gerardo
    Gonzales, Isidro
    Saavedra, Herbert
    Bustos, Javier
    Garcia, Hector H.
    Loeb, Jeffery A.
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2017, 97 (05): : 11 - 11
  • [35] Seizures in Pregnancy- A Rare Case of Neurocysticercosis Mimicking Eclampsia
    Kshirsagar, Pooja Chandrakant
    Acharya, Neema
    Acharya, Sourya
    Tembhare, Amardeep
    JOURNAL OF EVOLUTION OF MEDICAL AND DENTAL SCIENCES-JEMDS, 2020, 9 (12): : 1012 - 1014
  • [36] Active neurocysticercosis brain lesions predict risk of future seizures
    Lawrence, D
    LANCET, 2002, 360 (9349): : 1947 - 1947
  • [37] Electroclinical characteristics of new-onset seizures associated with neurocysticercosis
    Mehta, Sahil
    Singh, Gagandeep
    NEUROLOGY INDIA, 2014, 62 (02) : 159 - 163
  • [38] PATHOGENESIS OF SEIZURES IN NEUROCYSTICERCOSIS: FROM CYSTICERCOTIC LESIONS TO SEIZURE SEMIOLOGY
    Duque, Kevin R.
    Bustos, Javier A.
    Gonzales, Isidro
    Pretell, Javier
    Garcia, Hector H.
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2017, 95 (05): : 142 - 142
  • [39] Neurocysticercosis as an important differential of seizures in pregnancy: Two case reports
    Singhal S.R.
    Nanda S.
    Singhal S.K.
    Journal of Medical Case Reports, 5 (1)
  • [40] SEIZURES IN DOGS .2. EXTRACEREBRAL CAUSES OF SEIZURES
    STEFFEN, F
    JAGGY, A
    PRAKTISCHE TIERARZT, 1995, 76 (03): : 191 - &
12345