Self-assembly of protein-DNA superstructures for alkaline phosphatase detection in blood

被引：6
|
作者：
Chang, Yangyang [1 ]
Zhang, Qian [1 ]
Xue, Wei [1 ]
Wu, Yanfang [2 ]
Liu, Yi [3 ]
Liu, Meng [1 ]
机构：
[1] Dalian Univ Technol, Sch Environm Sci & Technol, Key Lab Ind Ecol & Environm Engn,Minist Educ, Dalian POCT Lab, Dalian 116024, Peoples R China
[2] Univ New South Wales, Sch Chem, Sydney, NSW 2052, Australia
[3] Dalian Med Univ, Dept Neurol, Dalian Municipal Cent Hosp, Dalian 116033, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 23期
关键词：
37;
D O I：
10.1039/d3cc00228d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We designed a paper-based analytical device by integrating horseradish peroxidase (HRP)-encapsulated 3D DNA for visual detection of alkaline phosphatase (ALP). This device allows on-paper sample pre-treatment, target recognition and signal readout, enabling simple (without additional pre-treatment of blood samples) and rapid (within 23 min) determination of ALP in clinical samples.
引用
收藏
页码：3399 / 3402
页数：4
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