A new methodology for the synthesis of highly functionalized pyrazol-5-one derivatives: A novel rearrangement

被引：0
|
作者：
Al -Sheikh, Mariam A. [1 ]
机构：
[1] Jeddah Univ, Fac Sci Al Faisaliah, Dept Chem, Jeddah 21493, Saudi Arabia
来源：
TETRAHEDRON LETTERS | 2023年 / 123卷
关键词：
Pyrazolone; Heterocyclic; Diethyl; 2; 5-dihydroxyterephthalat; Diazonium salts; Coupling reaction; BIOLOGICAL EVALUATION; PHARMACOLOGICAL EVALUATION; HETEROCYCLIC SYNTHESIS; INHIBITORS; ANALOGS; DESIGN; ESTERS; SAR;
D O I：
10.1016/j.tetlet.2023.154402
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The new derivatives of ethyl 1-aryl-5-oxo-4-(2-arylhydrazineylidene)-4,5-dihydro-1H-pyrazole-3-car-boxylates 8a-f were readily prepared, in one step, by coupling diethyl 2,5-dihydroxy-terephthalat (2) with diazonium salts 7a-f. The proposed mechanism of this novel one-step reaction and structure eluci-dation of the products were discussed.@2023 Elsevier Ltd. All rights reserved.
引用
收藏
页数：5
相关论文
共 50 条
  • [21] Synthesis of novel 5-methyl pyrazol-3-one derivatives and their in vitro cytotoxic evaluation
    Dube, Pritam N.
    Bule, Shweta S.
    Ushir, Yogesh V.
    Kumbhare, Manoj R.
    Dighe, Pravin R.
    MEDICINAL CHEMISTRY RESEARCH, 2015, 24 (03) : 1070 - 1076
  • [22] Synthesis of novel 5-methyl pyrazol-3-one derivatives and their in vitro cytotoxic evaluation
    Pritam N. Dube
    Shweta S. Bule
    Yogesh V. Ushir
    Manoj R. Kumbhare
    Pravin R. Dighe
    Medicinal Chemistry Research, 2015, 24 : 1070 - 1076
  • [23] A new alternative for the synthesis of highly functionalized phosphoryl derivatives
    Kraiem, H.
    Amri, H.
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2007, 182 (11) : 2555 - 2564
  • [24] Role of some pyrazol-5-one derivatives as corrosion inhibitors for 316L stainless steel in 1 M HCl
    Fouda, A. S.
    El-Ewady, G. Y.
    Fathy, S.
    DESALINATION AND WATER TREATMENT, 2013, 51 (10-12) : 2202 - 2213
  • [25] Novel Zn(II) complexes of 1,3-diphenyl-4-(arylazo)pyrazol-5-one derivatives: Synthesis, spectroscopic properties, DFT calculations and first order nonlinear optical properties
    Abdel-Latif, Samir A.
    Mohamed, Adel A.
    JOURNAL OF MOLECULAR STRUCTURE, 2018, 1156 : 712 - 725
  • [26] A methodology for the synthesis of highly functionalized 2- and 4-aminoquinoline derivatives
    Hwang, Bo Hyun
    Park, Sung Hee
    Choi, Eun Bok
    Pak, Chwang Siek
    Lee, Hyeon Kyu
    TETRAHEDRON, 2008, 64 (28) : 6698 - 6704
  • [27] One-pot regioselective synthesis of highly functionalized chromone derivatives
    Bam, Radha
    Chalifoux, Wesley
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [28] Synthesis of new trifluoromethyl-containing 1-(3,5-dialkyl-4-hydroxybenzyl)-pyrazole and -pyrazol-5-one deriatives and their corresponding aroxyls
    Dinoiu, V
    Lü, JM
    JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2006, 71 (04) : 323 - 330
  • [29] Rapid and efficient synthesis of 4-substituted pyrazol-5-one under microwave irradiation in solvent-free conditions
    Zahran, Magdy A. -H.
    El-Essawy, Farag A-A.
    Yassin, Sallah M.
    Salem, Tarek A-R.
    Boshta, Nader M.
    ARCHIV DER PHARMAZIE, 2007, 340 (11) : 591 - 598
  • [30] Design, synthesis, antimicrobial evaluations and in silico studies of novel pyrazol-5(4H)-one and 1H-pyrazol-5-ol derivatives
    Pham, Em Canh
    Tuong Vi Le Thi
    Phan, Long Tieu
    Nguyen, Huong-Giang T.
    Le, Khanh N. B.
    Tuyen Ngoc Truong
    ARABIAN JOURNAL OF CHEMISTRY, 2022, 15 (03)
12345