Langerhans Cell Histiocytosis Showed Intense Uptake of 68Ga-FAPI

被引：4
|
作者：
Pan, Qingqing [1 ,2 ]
Zhang, Hongzhe [1 ,2 ]
Cao, Xinxin [3 ]
Li, Jian [3 ]
Luo, Yaping [1 ,2 ]
机构：
[1] Chinese Acad Med Sci & Peking Union Med Coll Hosp, Dept Nucl Med, 1 Shuaifuyuan Wangfujing, Beijing 100730, Peoples R China
[2] Beijing Key Lab Mol Targeted Diag & Therapy Nucl M, Beijing, Peoples R China
[3] Chinese Acad Med Sci & Peking Union Med Coll Hosp, Dept Hematol, Beijing, Peoples R China
来源：
CLINICAL NUCLEAR MEDICINE | 2023年 / 48卷 / 10期
基金：
北京市自然科学基金;
关键词：
Langerhans cell histiocytosis; Ga-68-FAPI; PET/CT;
D O I：
10.1097/RLU.0000000000004786
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A 23-year-old man was recently diagnosed with Langerhans cell histiocytosis (LCH). 68Ga-FAPI PET/CT showed multiple lesions with intense FAPI uptake in the axial and appendicular skeleton with lytic or mixed bone destruction, consistent with osseous lesions of LCH. FAPI-avid foci around the right atrium and inferior vena cava, as well as micronodules and thin-walled cysts in the lungs, were also noted, possibly also involvement of LCH. This case suggested that 68Ga-FAPI PET/CT may have the potential to be applied in evaluation of LCH. © Wolters Kluwer Health, Inc. All rights reserved.
引用
收藏
页码：894 / 895
页数：2
相关论文
共 50 条
  • [41] 68Ga-Labeled Fibroblast Activation Protein Inhibitor (68Ga-FAPI) PET for Pancreatic Adenocarcinoma: Data from the 68Ga-FAPI PET Observational Trial
    Kessler, Lukas
    Hirmas, Nader
    Pabst, Kim M.
    Hamacher, Rainer
    Ferdinandus, Justin
    Schaarschmidt, Benedikt M.
    Milosevic, Aleksandar
    Nader, Michael
    Umutlu, Lale
    Uhl, Waldemar
    Reinacher-Schick, Anke
    Lugnier, Celine
    Witte, David
    Niedergethmann, Marco
    Herrmann, Ken
    Fendler, Wolfgang P.
    Siveke, Jens T.
    JOURNAL OF NUCLEAR MEDICINE, 2023, 64 (12) : 1910 - 1917
  • [42] [68Ga]Ga-FAPI versus [18F]FDG PET/CT in the evaluation of Langerhans cell histiocytosis
    Guo, Linlin
    Shen, Guohua
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2024, 51 (08) : 2520 - 2521
  • [43] 68Ga-FAPI and 18F-FDG Uptake in a Patient With Esophageal Candida Infection
    Chen, Xi
    Liu, Mengna
    Yang, Liping
    Shu, Qiaoqiao
    Cai, Liang
    CLINICAL NUCLEAR MEDICINE, 2024, 49 (01) : 83 - 85
  • [44] 68Ga-FAPI PET/CT imaging in a patient with thyroiditis
    Yue Zhou
    Jing He
    Yue Chen
    Endocrine, 2021, 73 : 485 - 486
  • [45] Increased 68Ga-FAPI Uptake in Avascular Necrosis of Femoral Head in a Patient With Nasopharyngeal Carcinoma
    Liu, Huipan
    Fu, Wenhui
    Yang, Xiao
    Chen, Yue
    CLINICAL NUCLEAR MEDICINE, 2022, 47 (05) : 449 - 450
  • [46] Increased 68Ga-FAPI Uptake of Symptomatic Intracranial Atherosclerotic Plaque Revealed by PET/MR
    Yang, Qiao
    Zhang, Zongmuyu
    Li, Mingli
    Xu, Wei-Hai
    Huo, Li
    CLINICAL NUCLEAR MEDICINE, 2022, 47 (05) : 469 - 470
  • [47] Mesenteric Mesonephric Adenocarcinoma on 68Ga-FAPI PET/CT
    Liu, Huipan
    Chen, Yue
    CLINICAL NUCLEAR MEDICINE, 2023, 48 (02) : 197 - 198
  • [48] 68Ga-FAPI PET/CT imaging in a patient with thyroiditis
    Zhou, Yue
    He, Jing
    Chen, Yue
    ENDOCRINE, 2021, 73 (02) : 485 - 486
  • [49] Elevated 68Ga-FAPI Activity in Tailgut Cyst Adenocarcinoma
    Huang, Yilin
    Ou, Lei
    Zeng, Chengrun
    Chen, Xiaoliang
    CLINICAL NUCLEAR MEDICINE, 2024, 49 (11) : 1044 - 1045
  • [50] Diffuse high uptake of 68Ga-FAPI in both kidneys helps with diagnosis of kidney diseases
    Zhong, X.
    Cheng, J.
    Su, M.
    Zhang, W.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2023, 50 (SUPPL 1) : S687 - S688
12345