Contextual drive of neuronal responses in mouse V1 in the absence of feedforward input

被引:10
|
作者
Kirchberger, Lisa [1 ]
Mukherjee, Sreedeep [1 ]
Self, Matthew W. [1 ]
Roelfsema, Pieter R. [1 ,2 ,3 ,4 ]
机构
[1] Netherlands Inst Neurosci, Dept Vis & Cognit, Meibergdreef 47, NL-1105 BA Amsterdam, Netherlands
[2] Vrije Univ Amsterdam, Ctr Neurogenom & Cognit Res, Dept Integrat Neurophysiol, Amsterdam, Netherlands
[3] Acad Med Ctr, Dept Psychiat, Amsterdam, Netherlands
[4] Sorbonne Univ, Inst Natl Sante & Rech Med, Inst Vis, Ctr Natl Rech Sci, F-75012 Paris, France
关键词
CLASSICAL RECEPTIVE-FIELD; FIGURE-GROUND SEGREGATION; VISUAL-CORTEX; SURROUND SUPPRESSION; FILLING-IN; CONNECTIONS; VISION; AREA; INTERNEURONS; INHIBITION;
D O I
10.1126/sciadv.add2498
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Neurons in the primary visual cortex (V1) respond to stimuli in their receptive field (RF), which is defined by the feedforward input from the retina. However, V1 neurons are also sensitive to contextual information outside their RF, even if the RF itself is unstimulated. Here, we examined the cortical circuits for V1 contextual responses to gray disks superimposed on different backgrounds. Contextual responses began late and were strongest in the feedback-recipient layers of V1. They differed between the three main classes of inhibitory neurons, with particularly strong contextual drive of VIP neurons, indicating a contribution of disinhibitory circuits to contex-tual drive. Contextual drive was strongest when the gray disk was perceived as figure, occluding its background, rather than a hole. Our results link contextual drive in V1 to perceptual organization and provide previously unknown insight into how recurrent processing shapes the response of sensory neurons to facilitate figure perception.
引用
收藏
页数:13
相关论文
共 50 条
  • [21] Saccades differentially modulate human LGN and V1 responses in the presence and absence of visual stimulation
    Sylvester, R
    Haynes, JD
    Rees, G
    CURRENT BIOLOGY, 2005, 15 (01) : 37 - 41
  • [22] Surround modulation of neuronal responses in V1 is as stable over time as responses to direct stimulation of receptive fields
    Pasca, Sergiu P.
    Singer, Wolf
    Nikolic, Danko
    CORTEX, 2010, 46 (09) : 1199 - 1203
  • [23] Ocular dominance-dependent binocular combination of monocular neuronal responses in macaque V1
    Zhang, Sheng-Hui
    Zhao, Xing-Nan
    Jiang, Dan-Qing
    Tang, Shi-Ming
    Yu, Cong
    ELIFE, 2024, 13
  • [24] The Spatial Precision of Contextual Feedback Signals in Human V1
    Petro, Lucy S.
    Smith, Fraser W.
    Abbatecola, Clement
    Muckli, Lars
    BIOLOGY-BASEL, 2023, 12 (07):
  • [25] Contextual modulation in V1: the Rossi-Zipser controversy
    E. Corthout
    H. Supèr
    Experimental Brain Research, 2004, 156 : 118 - 123
  • [26] The time course of contextual modulation in macaque V1 neurons
    Bair, W
    Cavanaugh, JR
    Movshon, JA
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1999, 40 (04) : S201 - S201
  • [27] The relation between V1 neuronal responses and eye movement-like stimulus presentations
    Richmond, BJ
    Hertz, JA
    Gawne, TJ
    COMPUTATIONA L NEUROSCIENCE: TRENDS IN RESEARCH 1999, 1999, : 247 - 254
  • [28] The relation between V1 neuronal responses and eye movement-like stimulus presentations
    Richmond, BJ
    Hertz, JA
    Gawne, TJ
    NEUROCOMPUTING, 1999, 26-7 : 247 - 254
  • [29] Optical Imaging of Contextual Interactions in V1 of the Behaving Monkey
    Kinoshita, Masaharu
    Gilbert, Charles D.
    Das, Aniruddha
    JOURNAL OF NEUROPHYSIOLOGY, 2009, 102 (03) : 1930 - 1944
  • [30] Contextual modulation in V1:: The Rossi-Zipser controversy
    Corthout, E
    Supèr, H
    EXPERIMENTAL BRAIN RESEARCH, 2004, 156 (01) : 118 - 123