The Drug Paracetamol and Sodium Carboxymethyl Cellulose Interactions and Their Importances for Pharmaceutical and Biomedical Applications

被引：3
|
作者：
Moumni, Hamida [1 ]
Cherif, Emna [1 ,2 ]
机构：
[1] Univ Tunis El Manar, Fac Sci Tunis, Lab Phys Matiere Molle & Phys Fluides LR99ES16, Tunis, Tunisia
[2] Univ Tunis El Manar, Fac Sci Tunis, Lab Phys Matiere Molle & Phys Fluides LR99ES16, Tunis 2092, Tunisia
来源：
JOURNAL OF MACROMOLECULAR SCIENCE PART B-PHYSICS | 2024年 / 63卷 / 11期
关键词：
Activation energy; dynamic viscosity; efferalgan; paracetamol; sodium carboxymethyl cellulose; FATTY-ACID PRODUCTION; POLYELECTROLYTE COMPLEXES; SUPERABSORBENT COMPOSITE; CHARGED POLYELECTROLYTES; SEEDS; POLYSACCHARIDE; DELIVERY; CALCIUM; PH;
D O I：
10.1080/00222348.2024.2316478
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The interactions of naturally occurring polymers and medicaments, sodium carboxymethyl cellulose (Na-CMC) and Paracetamol (PCM), have attracted the interest of researchers in a variety of biomedical and pharmaceutical applications areas, such as drug delivery, cosmetics and tissue engineering. In our research described here, the effects of temperature and concentration of Na-CMC/PCM/water (W) mixed solutions were studied at various temperatures ranging from 20 degrees C to 45 degrees C. We highlighted that different regions can be distinguished in the aqueous Na-CMC/PCM/W complexes, depending on the composition and electrostatic interactions of the solutions, which are associated with significantly different phase behaviors.
引用
收藏
页码：1189 / 1202
页数：14
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