Polysaccharides from marine biological resources and their anticancer activity on breast cancer

被引:5
|
作者
Yang, Shengfeng [1 ]
Li, Dacheng [2 ]
Liu, Weili [2 ]
Chen, Xiaolin [3 ]
机构
[1] Qingdao Univ, Qingdao Canc Hosp, Dept Oncol, Affiliated Qingdao Cent Hosp, Qingdao, Peoples R China
[2] Qingdao Univ, Dept Nucl Med, Affiliated Hosp, Qingdao, Peoples R China
[3] Chinese Acad Sci, Inst Oceanol, Beijing, Peoples R China
来源
RSC MEDICINAL CHEMISTRY | 2023年 / 14卷 / 06期
关键词
MOLECULAR-WEIGHT FUCOIDAN; IN-VITRO; BROWN SEAWEEDS; SULFATED POLYSACCHARIDE; UNDARIA-PINNATIFIDA; FUCUS-VESICULOSUS; APOPTOSIS; CELLS; MDA-MB-231; INDUCTION;
D O I
10.1039/d3md00035d
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In recent decades, natural products from marine organisms have been widely studied for the treatment of various breast cancers. Among them, polysaccharides have been favored by researchers because of their good effects and safety. In this review, polysaccharides from marine algae including macroalgae and microalgae, chitosan, microorganisms such as marine bacteria and fungi, and starfish are addressed. Their anticancer activities on different breast cancers and action mechanisms are discussed in detail. In general, polysaccharides from marine organisms are potential sources of low side-effect and high efficiency anticancer drugs for development. However, further research on animals and clinical research are needed.
引用
收藏
页码:1049 / 1059
页数:11
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