One-Step Synthesis of Benzophosphole Derivatives from Arylalkynes by Phosphenium-Dication-Mediated Sequential C-P/C-C Bond Forming Reaction

被引：12

作者：

Nishimura, Kazutoshi ^{[1
]}

Xu, Shibo ^{[2
]}

Nishii, Yuji ^{[1
]}

Hirano, Koji ^{[1
,2
]}

机构：

[1] Osaka Univ, Grad Sch Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan

[2] Osaka Univ, Inst Open & Transdisciplinary Res Initiat ICS OTRI, Innovat Catalysis Sci Div, Suita, Osaka 5650871, Japan

来源：

ORGANIC LETTERS | 2023年

关键词：

FRIEDEL-CRAFTS REACTION; FACILE SYNTHESIS; OXIDES; CYCLIZATION; RING;

D O I：

10.1021/acs.orglett.3c00263

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A metal-free, phosphenium-dication-mediated sequential C-P and C-C bond forming reaction has been developed. This protocol can provide concise access to the (di)benzophosphole derivatives in one synthetic operation from the readily available and simple arylalkynes and phosphinic acids. Application to the multiple cyclization reaction and the fully intermolecular three-component coupling-type reaction are also described.

引用

页码：1503 / 1508

页数：6

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