Two New Anti-Tobacco Mosaic Virus Quinolin-2(1H)-Ones from the Twigs of Cassia auriculata

被引：2
|
作者：
Zheng, Chao-Pei [1 ,2 ]
Xiong, Wen [2 ]
Zhang, Ling-Fang [1 ]
Jin, Wang [2 ]
Zhang, Jian-Duo [2 ]
Li, Yin-Ke [1 ,2 ]
Hu, Qiu-Fen [1 ,2 ]
Min, Zhou [1 ]
Kong, Guang-Hui [3 ]
Ye, Yan-Qing [1 ]
Wu, Yu-Ping [3 ]
机构：
[1] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, Kunming 650031, Peoples R China
[2] China Tobacco Yunnan Ind Co Ltd, Yunnan Key Lab Tobacco Chem, Kunming 650231, Peoples R China
[3] Yunnan Acad Tobacco Agr Sci, Kunming 650031, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2023年 / 59卷 / 01期
基金：
中国国家自然科学基金;
关键词：
quinolin-2(1H)-one; Cassia auriculata; anti-tobacco mosaic virus activity; CONSTITUENTS; ALKALOIDS; PRODUCTS; ALATA; SEEDS; LINN;
D O I：
10.1007/s10600-023-03928-6
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Two new quinolin-2(1H)-ones, 7-methoxy-6-methyl-4-(4-methylfuran-2-yl)quinolin-2(1H)-one (1) and 7-hydroxy-6-methyl-4-(4-methylfuran-2-yl)quinolin-2(1H)-one (2), were isolated from the twigs of Cassia auriculata. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 exhibited potential anti-TMV activity with inhibition rates of 38.4 and 49.2%, respectively.
引用
收藏
页码：107 / 110
页数：4
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