Two New Flavones from Cassia pumila and Their Anti-Tobacco Mosaic Virus Activity

被引：7
|
作者：
Kong, Wei-Song [1 ]
Xing, Huan-Huan [1 ,2 ]
Li, Jing [1 ]
Ye, Lin [1 ]
Liu, Xin [1 ]
Li, Yan-Ping [4 ]
Rao, Gao-Xiong [4 ]
Zhou, Min [1 ]
Guangyu-Yang [1 ]
Hu, Qiu-Fen [1 ,2 ]
Li, Yin-Ke [1 ,3 ]
Li, Xue-Mei [1 ]
机构：
[1] China Tobacco Yunnan Ind Co Ltd, Kunming 650231, Yunnan, Peoples R China
[2] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, Kunming 650031, Yunnan, Peoples R China
[3] Yuxi Normal Univ, Coll Resource & Environm, Yuxi 653100, Peoples R China
[4] Yunnan Univ Tradit Chinese Med, Coll Pharmaceut Sci, Kunming 650500, Yunnan, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2018年 / 54卷 / 06期
基金：
中国国家自然科学基金;
关键词：
flavones; Cassia pumila; anti-tobacco mosaic virus (anti-TMV) activity; FISTULA; SIAMEA; DERIVATIVES; STEMS; BARK; BIOACTIVITIES; ALKALOIDS; CHROMONES; SEEDS;
D O I：
10.1007/s10600-018-2552-3
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Two new flavones, 8-hydroxy-7-(3-hydroxypropyl)-2-methoxyflavone (1) and 8-hydroxy-7-(2-hydroxyethyl)-2-methoxyflavone (2), together with four known flavones (3-6), were isolated from the whole plants of Cassia pumila. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 have potential anti-TMV activities with inhibition rates of 30.2% and 28.2%, respectively.
引用
收藏
页码：1048 / 1051
页数：4
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