GASTRIC NEUROENDOCRINE TUMOR: WHEN SURGICAL TREATMENT IS INDICATED?

BACKGROUND: Gastric neuroendocrine tumors are a heterogeneous group of neoplasms that produce bioactive substances. Their treatment varies according to staging , bricio Fer eira COELHO3 Paulo HERMAN3 classification, using endoscopic techniques, open surgery, chemotherapy, radiotherapy , drugs analogous to somatostatin. AIMS: To identify and review cases of gastric neuroendocrine neoplasia submitted to surgical treatment. METHODS: Review of surgically treated patients from 1983 to 2018.RESULTS: Fifteen patients were included, predominantly female (73.33%), with a mean age UMO -Racipnal O tratamento de es olha para pacien es com hipertensao portal of 55.93 years. The most common symptom was epigastric pain (93.3%), and the mean time of esquistos moc com sangramento de vrizs e a dconxa azigo-portal mais symptom onset wa s 10.07 months. The preoperative upper digestive endo scopy (UDE) indicated esplenectomia (DAPE) asociada a e apa endoscopica. Porem estudo mostr m aumeno a predominance of cases with 0 to 1 lesion (60%), sizing >= 1.5 cm (40%), located in the gastric do calibre das va izes em alguns pacientes durante o seguimento em longo p azo Objetivp antrum (53.33%), with ulceration (60%), and Borrmann III (33.33%) classification. The assessment Av liar o mpacto da DAPE e tra amento endoscopico pos operatorio no comportamento of the surgical specimen indicated a predominance of invasive neuroendocrine tumors (60%), with angiolymphatic invasion in most cases (80%). Immunohistochemistry for chromogranin A was das varizes esofagicas e recidiva hemorragica, de pa ientes esquistossomoticos. Metodos: positive in 60% of cases and for synaptophysin in 66.7%, with a predominant Ki-67 index between Foram es udados 36 pacientes com seguimento superior cinco anos, distribuidos em 0 and 2%. Metastasis was observed in 20% of patients. The surgica l procedure most performed was dois grupo: queda da p essao portal abaixo de 30% e acia d 30% omparados com subtotal gastrectomy with Roux-en-Y reconstruction (53.3%). Tumor re currence occurred in 20% o f calibre das varizes esofagcas no pos-operatorio precoce e tardio lem do indice de recidiva cases and a new treatment was required in 26.67%.CONCLUSIONS: Gastric neuroendocrine tumors hemorragica Resultadps have a low incidence in the general population, and surgical treatment is indicated for advanced lesions. The study of its management gains importance in view of the specificities of each case and esofagicas que, durante o seguimento aumentaram de calibre e f the need for adequate conduct to prevent recurrences and complications.