Enriching the FIDEO ontology with food-drug interactions from online knowledge sources

被引:1
|
作者
Azzi, Rabia [1 ,2 ]
Bordea, Georgeta [1 ,3 ]
Griffier, Romain [1 ,2 ]
Nikiema, Jean Noel [4 ]
Mougin, Fleur [1 ]
机构
[1] Univ Bordeaux, INSERM, BPH, F-33000 Bordeaux, France
[2] CHU Bordeaux, Serv Informat Med, F-33000 Bordeaux, France
[3] Univ La Rochelle, L3i, F-17000 La Rochelle, France
[4] Univ Montreal, Sch Publ Hlth, Dept Management Evaluat & Hlth Policy, Montreal, PQ, Canada
关键词
Biomedical ontology; Food-drug interactions; Adverse drug effects; FAIR principles; GRAPEFRUIT JUICE;
D O I
10.1186/s13326-024-00302-5
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The increasing number of articles on adverse interactions that may occur when specific foods are consumed with certain drugs makes it difficult to keep up with the latest findings. Conflicting information is available in the scientific literature and specialized knowledge bases because interactions are described in an unstructured or semi-structured format. The FIDEO ontology aims to integrate and represent information about food-drug interactions in a structured way. This article reports on the new version of this ontology in which more than 1700 interactions are integrated from two online resources: DrugBank and Hedrine. These food-drug interactions have been represented in FIDEO in the form of precompiled concepts, each of which specifies both the food and the drug involved. Additionally, competency questions that can be answered are reviewed, and avenues for further enrichment are discussed.
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收藏
页数:14
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