Oncolytic Adenovirus Armed with Interferon Alpha Elicits Systemic Antitumor Immunity in Syrian Hamster Pancreatic Cancer Models

被引：0
|
作者：
Inoko, Kazuho [1 ]
Romanenko, Margarita [1 ]
Robert, Sacha [1 ]
Shinoda, Shuhei [1 ]
Sato-Dahlman, Mizuho [1 ]
Jacobsen, Kari [1 ]
Noguchi, Takuro [2 ]
Yamamoto, Masato [1 ]
Davydova, Julia [1 ]
机构：
[1] Univ Minnesota, Dept Surg, Minneapolis, MN USA
[2] Hokkaido Univ, Dept Med Oncol, Sapporo, Hokkaido, Japan
来源：
MOLECULAR THERAPY | 2023年 / 31卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
1643
引用
收藏
页码：771 / 771
页数：1
相关论文
共 50 条
  • [21] Effect of Preexisting Immunity on Oncolytic Adenovirus Vector INGN 007 Antitumor Efficacy in Immunocompetent and Immunosuppressed Syrian Hamsters
    Dhar, Debanjan
    Spencer, Jacqueline F.
    Toth, Karoly
    Wold, William S. M.
    JOURNAL OF VIROLOGY, 2009, 83 (05) : 2130 - 2139
  • [22] Oncolytic Adenovirus Regulated by Tumor Microevnrionment-Targeted Hybrid Promoter Elicits Potent Antitumor Effect against Desmoplastic Pancreatic Cancer
    Kim, In-Wook
    Li, Yan
    Hong, JinWoo
    Oh, Joung-Eun
    Yoon, A-Rum
    Yun, Chae-Ok
    MOLECULAR THERAPY, 2018, 26 (05) : 331 - 331
  • [23] Dendritic cell maturation is induced by p53-armed oncolytic adenovirus via tumor-derived exosomes enhancing systemic antitumor immunity
    Tomoko Ohtani
    Shinji Kuroda
    Nobuhiko Kanaya
    Yoshihiko Kakiuchi
    Kento Kumon
    Masashi Hashimoto
    Chiaki Yagi
    Ryoma Sugimoto
    Satoru Kikuchi
    Shunsuke Kagawa
    Hiroshi Tazawa
    Yasuo Urata
    Toshiyoshi Fujiwara
    Cancer Immunology, Immunotherapy, 74 (1)
  • [24] Evaluation of apoptogenic adenovirus type 5 oncolytic vectors in a Syrian hamster head and neck cancer model
    S Vijayalingam
    M Kuppuswamy
    T Subramanian
    F F Strebeck
    C L West
    M Varvares
    G Chinnadurai
    Cancer Gene Therapy, 2014, 21 : 228 - 237
  • [25] Evaluation of apoptogenic adenovirus type 5 oncolytic vectors in a Syrian hamster head and neck cancer model
    Vijayalingam, S.
    Kuppuswamy, M.
    Subramanian, T.
    Strebeck, F. F.
    West, C. L.
    Varvares, M.
    Chinnadurai, G.
    CANCER GENE THERAPY, 2014, 21 (06) : 228 - 237
  • [26] EFFICIENT SYSTEMIC TREATMENT WITH MESOTHELIN-TARGETED ONCOLYTIC ADENOVIRUS IN PANCREATIC CANCER
    Sato-Dahlman, Mizuko
    Jacobsen, Kati
    Yanagiba, Chikako
    Yamamoto, Masato
    GASTROENTEROLOGY, 2021, 160 (06) : S469 - S469
  • [27] Intratumoral adenovirus-mediated interferon alpha gene transfer induces regional direct cytotoxicity and possible systemic immunity against pancreatic cancer
    Aoki, K
    Ohashi, M
    Miura, Y
    Yoshida, K
    Ohnami, S
    Kitade, Y
    Yoshida, T
    MOLECULAR THERAPY, 2004, 9 : S363 - S363
  • [28] Efficacy of Systemic Administration of Mesothelin-Targeted Oncolytic Adenovirus in Pancreatic Cancer
    Sato-Dahlman, M.
    Hajeri, P.
    Jacobsen, K.
    Yanagiba, C.
    Yamamoto, M.
    PANCREAS, 2021, 50 (07) : 1095 - 1095
  • [29] Efficacy of Systemic Administration of Mesothelin-Targeted Oncolytic Adenovirus In Pancreatic Cancer
    Sato-Dahlman, Mizuho
    Hajeri, Praveensingh
    Jacobsen, Kari
    Yanagiba, Chikako
    Yamamoto, Masato
    MOLECULAR THERAPY, 2021, 29 (04) : 322 - 323
  • [30] Human adenovirus replicates in immunocompetent models of pancreatic cancer in Syrian hamsters
    Bortolanza, Sergia
    Alzuguren, Pilar
    Bunuales, Maria
    Qian, Cheng
    Prieto, Jesus
    Hernandez-Alcoceba, Ruben
    HUMAN GENE THERAPY, 2007, 18 (08) : 681 - 690
12345