With the continuous advancement of internet of things, big data, and artificial intelligence technologies, selfpowered functionalized applications have emerged as pivotal components in the realm of smart technology. Here, we present a flexible and environmentally sustainable wood-based triboelectric nanogenerator (W-TENG) that enables the self-powered functionalization of applications in the emerging smart field. By employing a straightforward yet effective approach utilizing natural balsa wood, the W-TENG exhibits remarkable flexibility, stability, and sensitivity. Notably, balsa wood possesses a lower weight, density, and crystallinity compared to other types of natural wood, resulting in thinner internal cell walls, larger individual cells and a more porous structure. These characteristics prove particularly advantageous for solvent modification. Given the prevalent use of wood materials in domestic construction, the energy-efficient W-TENG can be seamlessly integrated into various smart applications, including wireless switches, home flooring, and energy-saving lamps. Moreover, this integration offers several benefits such as cost-effectiveness, high durability, ease of processing, and environmental friendliness. This research not only expands the range of self-powered applications in the smart sector but also drives the development of eco-friendly W-TENG electronics.