FDG-Avid But Pentixafor-Negative in EBV-Associated T-Cell Lymphoproliferative Disorders

被引：2
|
作者：
Shu, Qiaoqiao [1 ,2 ,3 ]
He, Xubing [1 ,2 ,3 ]
Chen, Yue [1 ,2 ,3 ]
Cai, Liang [1 ,2 ,3 ]
机构：
[1] Southwest Med Univ, Dept Nucl Med, Affiliated Hosp, 25 TaiPing St, Luzhou 646000, Sichuan, Peoples R China
[2] Nucl Med & Mol Imaging Key Lab Sichuan Prov, Luzhou, Sichuan, Peoples R China
[3] Southwest Med Univ, Inst Nucl Med, Luzhou, Sichuan, Peoples R China
来源：
CLINICAL NUCLEAR MEDICINE | 2023年 / 48卷 / 08期
关键词：
hemophagocytic lymphohistiocytosis; lymphoproliferative disorders; F-18-FDG; Ga-68-pentixafor; PET/CT; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS;
D O I：
10.1097/RLU.0000000000004747
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
An 18-year-old woman with intermittent fever, pancytopenia, abnormal liver function, and enlarged lymph nodes and hepatosplenomegaly was clinically suspected as hemophagocytic lymphohistiocytosis. F-18-FDG PET/CT showed increased metabolism in multiple lymph nodes, which were highly suggestive of lymphoma. No increased CXCR4 expression in lymph nodes was demonstrated on Ga-68-pentixafor PET/CT. Subsequent right neck lymph node biopsy pathology revealed EBV-associated lymphoproliferative disorders. Our case shows that Ga-68-pentixafor PET/CT may have potential value in differentiating EBV-associated lymphoproliferative disorders from lymphomas.
引用
收藏
页码：714 / 715
页数：2
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