Dexamethasone for Tuberculous Meningitis in HIV-Positive Adults

被引：0

作者：

Ellis, Jayne ^{[1
]}

Meya, David B. ^{[2
]}

Cresswell, Fiona C. ^{[1
]}

Donovan, Joseph ^{[1
]}

Phu, Nguyen H. ^{[3
]}

Thwaites, Guy E. ^{[3
]}

机构：

[1] London Sch Hyg & Trop Med, London, England

[2] Infect Dis Inst, Kampala, Uganda

[3] Oxford Univ Clin Res Unit, Ho Chi Minh City, Vietnam

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2024年 / 390卷 / 04期

关键词：

CEREBROSPINAL-FLUID PLEOCYTOSIS;

D O I：

10.1056/NEJMc2313671

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To the Editor: Donovan et al. (Oct. 12 issue)(1) found that the use of adjunctive glucocorticoids was not associated with a significant reduction in death among persons with human immunodeficiency virus (HIV)-associated tuberculous meningitis (hazard ratio vs. placebo, 0.85; 95% confidence interval [CI], 0.66 to 1.10; P=0.22). We previously reported that acellular cerebrospinal fluid (CSF) is common in persons with HIV-associated tuberculous meningitis(2) and that a CSF white-cell count of less than 5 per microliter is associated with a risk of death that is four times as great as that with a white-cell count of more than 100 per microliter . . .

引用

页码：382 / 383

页数：2

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