Development of a complement C3 humanized rat as a new model for evaluating novel C3 inhibitors

被引:0
|
作者
Lin, Feng [1 ]
Zhang, Lingjun [1 ]
Yang, Maojing [1 ]
Hughes, Elizabeth [2 ]
Saunders, Thomas [2 ]
Chen, Jin [1 ]
机构
[1] Cleveland Clin, Immunol, Cleveland, OH USA
[2] Univ Michigan, Ann Arbor, MI USA
关键词
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
2725
引用
收藏
页数:3
相关论文
共 50 条
  • [21] Hereditary human complement C3 deficiency owing to reduced levels of C3 mRNA
    Ulbrich, AG
    Florido, MPC
    Nudelman, V
    Reis, ES
    Baracho, GV
    Isaac, L
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2001, 53 (06) : 622 - 626
  • [22] A novel mechanism for hypofibrinolysis in diabetes: the role of complement C3
    Hess, K.
    Schroeder, V
    Alzahrani, S.
    Mathai, M.
    Howell, G.
    Smith, K.
    Carter, A. M.
    Marx, N.
    Grant, P. J.
    Ajjan, R.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2011, 9 : 140 - 140
  • [23] A novel mechanism for hypofibrinolysis in diabetes: the role of complement C3
    Hess, K.
    Alzahrani, S. H.
    Mathai, M.
    Schroeder, V.
    Carter, A. M.
    Howell, G.
    Koko, T.
    Strachan, M. W. J.
    Price, J. F.
    Smith, K. A.
    Grant, P. J.
    Ajjan, R. A.
    DIABETOLOGIA, 2012, 55 (04) : 1103 - 1113
  • [24] A novel mechanism for hypofibrinolysis in diabetes: the role of complement C3
    K. Hess
    S. H. Alzahrani
    M. Mathai
    V. Schroeder
    A. M. Carter
    G. Howell
    T. Koko
    M. W. J. Strachan
    J. F. Price
    K. A. Smith
    P. J. Grant
    R. A. Ajjan
    Diabetologia, 2012, 55 : 1103 - 1113
  • [25] On Evaluating Resilience in C3 Systems
    Pflanz, Mark A.
    Levis, Alexander H.
    Insight, 1 (29-33): : 29 - 33
  • [26] Pharmacological characterization of the novel complement C3 inhibitor BI-C
    Kreideweiss, Stefan
    Sobieraj, Anna
    Scheifele, Fabian
    Jungmichel, Stephanie
    Richle, Philipp
    Reindl, Sophia
    Hoerer, Stefan
    Gupta, Pankaj
    Bakker, Remko
    Lenherr-Frey, Daniel
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2024, 65 (07)
  • [28] C3 glomerulopathy: A new complement-based entity
    de Lorenzo, A.
    Tallon, S.
    Hernandez-Sevillano, B.
    de Arriba, G.
    REVISTA CLINICA ESPANOLA, 2014, 214 (05): : 266 - 274
  • [29] Identification of anti-C3bBb antibodies enhancing the formation of the C3 convertase: a new mechanism of dysregulation of the complement in C3 glomerulopathy
    Roquigny, Julia
    Mandaviy, Marion
    Chauvet, Sophie
    Fremeaux-Bacchi, Veronique
    MOLECULAR IMMUNOLOGY, 2022, 141 : 182 - 183