Rhodium-Catalyzed Intramolecular Cyclization to Synthesize 2-Aminobenzofurans via Carbene Metathesis Reactions

被引：3
|
作者：
Li, Xue [1 ,2 ]
Sheng, Heyun [1 ,2 ]
Song, Qiuling [1 ,2 ,3 ,4 ]
机构：
[1] Huaqiao Univ, Coll Chem Engn, Inst Next Generat Matter Transformat, Xiamen 361021, Fujian, Peoples R China
[2] Huaqiao Univ, Coll Mat Sci Engn, Xiamen 361021, Fujian, Peoples R China
[3] Fuzhou Univ, Coll Chem, Key Lab Mol Synth & Funct Discovery Fijian Prov Un, Fuzhou 350108, Fujian, Peoples R China
[4] Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Henan, Peoples R China
来源：
ORGANIC LETTERS | 2023年 / 25卷 / 12期
基金：
中国国家自然科学基金;
关键词：
ALKYNES; ACCESS; INSERTION; CYCLOADDITION; CASCADES; TRANSANNULATION; CYCLOPROPENES; CONSTRUCTION; DERIVATIVES; BENZOFURAN;
D O I：
10.1021/acs.orglett.3c00539
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Herein, we report a new method of synthesizing of 2-aminobenzofuran 3-enes via the formal C-S insertion reaction of alkyne-tethered diazo compounds. Metal carbene, as a kind of active synthetic intermediate, plays a very important role in organic synthesis. Through the carbene/alkyne metathesis strategy, a new donor carbene is produced in situ as a key intermediate, which has different reactions from the donor receptor carbene.
引用
收藏
页码：2113 / 2117
页数：5
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