Active ingredients of traditional Chinese medicine for enhancing the effect of tumor immunotherapy

被引:17
|
作者
Yang, Chao [1 ]
Li, Dan [2 ]
Ko, Chung-Nga [3 ]
Wang, Kai [4 ]
Wang, Haiyong [5 ]
机构
[1] Zhejiang Ocean Univ, Inst Innovat & Applicat, Natl Engn Res Ctr Marine Aquaculture, Zhoushan, Zhejiang, Peoples R China
[2] Chengdu Univ Tradit Chinese Med, Sch Pharm, State Key Lab Southwestern Chinese Med Resources, Chengdu, Peoples R China
[3] Hong Kong Int Eye Care Grp, C MER Dennis Lam & Partners Eye Ctr, Hong Kong, Peoples R China
[4] Southwest Med Univ, Res Ctr Preclin Med, Luzhou, Peoples R China
[5] Shandong First Med Univ & Shandong Acad Med Sci, Shandong Canc Hosp & Inst, Dept Internal Med Oncol, Jinan, Peoples R China
来源
FRONTIERS IN IMMUNOLOGY | 2023年 / 14卷
基金
中国国家自然科学基金;
关键词
tumor immunity; immunomodulation; traditional Chinese medicine; active ingredients; antitumor immunotherapy; natural products; REGULATORY T-CELLS; LUNG-CANCER; ASTRAGALUS POLYSACCHARIDES; ANTITUMOR IMMUNITY; PD-L1; EXPRESSION; HERBAL MEDICINE; OVARIAN-CANCER; TRIPTOLIDE; APIGENIN; MICROENVIRONMENT;
D O I
10.3389/fimmu.2023.1133050
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Immunotherapy is a type of treatment that uses our own immune system to fight cancer. Studies have shown that traditional Chinese medicine (TCM) has antitumor activity and can enhance host immunity. This article briefly describes the immunomodulatory and escape mechanisms in tumors, as well as highlights and summarizes the antitumor immunomodulatory activities of some representative active ingredients of TCM. Finally, this article puts forward some opinions on the future research and clinical application of TCM, aiming to promote the clinical applications of TCM in tumor immunotherapy and to provide new ideas for the research of tumor immunotherapy using TCM.
引用
收藏
页数:11
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