Biodegradable Polymeric Microspheres as Drug Carriers for Anti-Microbial Agent
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Bansal, Nidhi
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K R Mangalam Univ, Sch Med & Allied Sci, Sohna Rd, Gurugram 122103, Haryana, IndiaK R Mangalam Univ, Sch Med & Allied Sci, Sohna Rd, Gurugram 122103, Haryana, India
Bansal, Nidhi
[1
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Rao, Komal
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K R Mangalam Univ, Sch Med & Allied Sci, Sohna Rd, Gurugram 122103, Haryana, IndiaK R Mangalam Univ, Sch Med & Allied Sci, Sohna Rd, Gurugram 122103, Haryana, India
Rao, Komal
[1
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Yadav, Nikita
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Starex Univ, Sch Pharmaceut Sci, Gurugram 122413, Haryana, IndiaK R Mangalam Univ, Sch Med & Allied Sci, Sohna Rd, Gurugram 122103, Haryana, India
Yadav, Nikita
[2
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Minocha, Neha
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Chitkara Univ, Sch Pharm, Baddi 174103, Himachal Prades, IndiaK R Mangalam Univ, Sch Med & Allied Sci, Sohna Rd, Gurugram 122103, Haryana, India
Minocha, Neha
[3
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机构:
[1] K R Mangalam Univ, Sch Med & Allied Sci, Sohna Rd, Gurugram 122103, Haryana, India
[2] Starex Univ, Sch Pharmaceut Sci, Gurugram 122413, Haryana, India
[3] Chitkara Univ, Sch Pharm, Baddi 174103, Himachal Prades, India
Introduction Microspheres, the novel drug delivery system that offers therapeutic alternatives to single-unit dosage forms, both conventional and quick release. Microspheres are solid microspheres having a diameter of 1-1000 mu m. Microspheres can be made utilising various procedures that vary in their effectiveness and dosage form administration when compared to standard dosage forms.Background The idea of targeted drug delivery is to concentrate the treatment in the target tissues while lowering the relative concentration of the drug in the non-target tissues. As a result, the medication is concentrated at the desired location. Thus, the medication has no effect on the tissues nearby. Therefore, by combining the drug with carrier particle like microspheres, nanoparticles, liposomes, niosomes, etc., that regulates the release and absorption characteristics of the drug, carrier technology offers an intelligent way for drug delivery.Results Microspheres are naturally biodegradable materials made of proteins or synthetic polymers that flow freely. Its formulation is approachable, maintaining the desired concentration at the site of interest without unfavorable effects and reliably delivering the drug to the target site with specificity.Conclusion Microspheres attracted a lot of interest for their sustained release as well as their ability to direct anti-cancer medications to the tumour using biodegradable polymers. Due to this, future drug delivery systems for innovative medications will heavily rely on microspheres.
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CSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, IndiaCSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Duggal, Shivali
Sharma, Shivani
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CSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, IndiaCSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Sharma, Shivani
Rai, Nikhil
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Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
CSIR Cent Drug Res Inst, Div Pharmaceut & Pharmacokinet, Council Sci & Ind Res, Lucknow 226031, IndiaCSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Rai, Nikhil
Chauhan, Divya
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Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
CSIR Cent Drug Res Inst, Div Pharmaceut & Pharmacokinet, Council Sci & Ind Res, Lucknow 226031, IndiaCSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Chauhan, Divya
Upadhyay, Vishal
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Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
CSIR Cent Drug Res Inst, Div Canc Biol, Council Sci & Ind Res, Lucknow 226031, IndiaCSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Upadhyay, Vishal
Srivastava, Swati
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CSIR Cent Drug Res Inst, Div Canc Biol, Council Sci & Ind Res, Lucknow 226031, IndiaCSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Srivastava, Swati
Porwal, Konica
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CSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, IndiaCSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Porwal, Konica
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Kulkarni, Chirag
Trivedi, Arun K.
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Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
CSIR Cent Drug Res Inst, Div Canc Biol, Council Sci & Ind Res, Lucknow 226031, IndiaCSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Trivedi, Arun K.
Gayen, Jiaur R.
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CSIR Cent Drug Res Inst, Div Pharmaceut & Pharmacokinet, Council Sci & Ind Res, Lucknow 226031, IndiaCSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Gayen, Jiaur R.
Mishra, Prabhat R.
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CSIR Cent Drug Res Inst, Div Pharmaceut & Pharmacokinet, Council Sci & Ind Res, Lucknow 226031, IndiaCSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Mishra, Prabhat R.
Chattopadhyay, Naibedya
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CSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, IndiaCSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Chattopadhyay, Naibedya
Pal, Subhashis
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CSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India
Emory Univ, Dept Med, Div Endocrinol Metab & Lipids, Atlanta, GA 30322 USA
SRM Inst Sci & Technol SRM IST, SRM Med Coll Hosp & Res Ctr, Div Med Res, Kattankulathur 603203, IndiaCSIR Cent Drug Res Inst, Council Sci & Ind Res, Div Endocrinol, Lucknow 226031, India