Biodegradable Polymeric Microspheres as Drug Carriers for Anti-Microbial Agent

被引:0
|
作者
Bansal, Nidhi [1 ]
Rao, Komal [1 ]
Yadav, Nikita [2 ]
Minocha, Neha [3 ]
机构
[1] K R Mangalam Univ, Sch Med & Allied Sci, Sohna Rd, Gurugram 122103, Haryana, India
[2] Starex Univ, Sch Pharmaceut Sci, Gurugram 122413, Haryana, India
[3] Chitkara Univ, Sch Pharm, Baddi 174103, Himachal Prades, India
关键词
Microspheres; cross-linking; encapsulation; therapeutic; controlled-release; liposomes; LOCUST BEAN GUM; SOLID LIPID NANOPARTICLES; IN-VITRO RELEASE; ALGINATE HYDROGELS; DELIVERY; MICROPARTICLES; MICROCAPSULES; ORGANIZATION; FORMULATION; SOLUBILITY;
D O I
10.2174/1574885518666230530095329
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Introduction Microspheres, the novel drug delivery system that offers therapeutic alternatives to single-unit dosage forms, both conventional and quick release. Microspheres are solid microspheres having a diameter of 1-1000 mu m. Microspheres can be made utilising various procedures that vary in their effectiveness and dosage form administration when compared to standard dosage forms.Background The idea of targeted drug delivery is to concentrate the treatment in the target tissues while lowering the relative concentration of the drug in the non-target tissues. As a result, the medication is concentrated at the desired location. Thus, the medication has no effect on the tissues nearby. Therefore, by combining the drug with carrier particle like microspheres, nanoparticles, liposomes, niosomes, etc., that regulates the release and absorption characteristics of the drug, carrier technology offers an intelligent way for drug delivery.Results Microspheres are naturally biodegradable materials made of proteins or synthetic polymers that flow freely. Its formulation is approachable, maintaining the desired concentration at the site of interest without unfavorable effects and reliably delivering the drug to the target site with specificity.Conclusion Microspheres attracted a lot of interest for their sustained release as well as their ability to direct anti-cancer medications to the tumour using biodegradable polymers. Due to this, future drug delivery systems for innovative medications will heavily rely on microspheres.
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页码:49 / 59
页数:11
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