Single-cell nanobody-based profiles of multiple epigenetic modalities and chromatin velocity

被引：0
|
作者：
Bartosovic, Marek [1 ]
Castelo-Branco, Goncalo [2 ]
机构：
[1] Stockholm Univ, Stockholm, Sweden
[2] Karolinska Inst, Stockholm, Sweden
来源：
NATURE BIOTECHNOLOGY | 2023年 / 41卷 / 06期
关键词：
D O I：
10.1038/s41587-022-01596-5
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Nanobody-Tn5 transposase fusion proteins enable detection of two histone marks and open chromatin regions at the same time, with single-cell resolution.
引用
收藏
页码：767 / 768
页数：2
相关论文
共 50 条
  • [41] Spatially mapped single-cell chromatin accessibility
    Thornton, Casey A.
    Mulqueen, Ryan M.
    Torkenczy, Kristof A.
    Nishida, Andrew
    Lowenstein, Eve G.
    Fields, Andrew J.
    Steemers, Frank J.
    Zhang, Wenri
    McConnell, Heather L.
    Woltjer, Randy L.
    Mishra, Anusha
    Wright, Kevin M.
    Adey, Andrew C.
    NATURE COMMUNICATIONS, 2021, 12 (01)
  • [42] Profiling single-cell chromatin accessibility in plants
    Marand, Alexandre P.
    Zhang, Xuan
    Nelson, Julie
    dos Reis, Pedro Augusto Braga
    Schmitz, Robert J.
    STAR PROTOCOLS, 2021, 2 (03):
  • [43] A single-cell chromatin map of human embryos
    Perez-Palacios, Raquel
    Bourc'his, Deborah
    NATURE CELL BIOLOGY, 2018, 20 (07) : 742 - 744
  • [44] Learning single-cell chromatin accessibility profiles using meta-analytic marker genes
    Kawaguchi, Risa Karakida
    Tang, Ziqi
    Fischer, Stephan
    Rajesh, Chandana
    Tripathy, Rohit
    Koo, Peter K.
    Gillis, Jesse
    BRIEFINGS IN BIOINFORMATICS, 2023, 24 (01)
  • [45] FITs: forest of imputation trees for recovering true signals in single-cell open chromatin profiles
    Sharma, Rachesh
    Pandey, Neetesh
    Mongia, Aanchal
    Mishra, Shreya
    Majumdar, Angshul
    Kumar, Vibhor
    NAR GENOMICS AND BIOINFORMATICS, 2020, 2 (04)
  • [46] Dynamics of epigenetic regulation at the single-cell level
    Bintu, Lacramioara
    Yong, John
    Antebi, Yaron E.
    McCue, Kayla
    Kazuki, Yasuhiro
    Uno, Narumi
    Oshimura, Mitsuo
    Elowitz, Michael B.
    SCIENCE, 2016, 351 (6274) : 720 - 724
  • [47] Nanobody-based sandwich reporter system for living cell sensing influenza A virus infection
    Cao, Jiali
    Zhong, Nicole
    Wang, Guosong
    Wang, Mingfeng
    Zhang, Baohui
    Fu, Baorong
    Wang, Yingbin
    Zhang, Tianying
    Zhang, Yali
    Yang, Kunyu
    Chen, Yixin
    Yuan, Quan
    Xia, Ningshao
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [48] Single-cell mRNA Profiles in PBMC
    Yang, Luning
    Zhang, Yihan
    Mitic, Nenad
    Keskin, Derin B.
    Zhang, Guang Lan
    Chitkushev, Lou
    Brusic, Vladimir
    2020 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE, 2020, : 1318 - 1323
  • [49] Single-cell profiles of CHD and CM
    Huynh, Karina
    NATURE REVIEWS CARDIOLOGY, 2022, 19 (09) : 575 - 575
  • [50] Single-cell profiles of CHD and CM
    Karina Huynh
    Nature Reviews Cardiology, 2022, 19 : 575 - 575
12345