Recent advances on cyclodepsipeptides: biologically active compounds for drug research

被引：4

作者：

Liu, Si-Xuan ^{[1
]}

Ou-Yang, Si-Yi ^{[1
]}

Lu, Yong-Fu ^{[1
]}

Guo, Chun-Lin ^{[1
]}

Dai, Si-Yang ^{[1
]}

Li, Chang ^{[1
,2
]}

Yu, Tian-Yi ^{[3
]}

Pei, Yue-Hu ^{[1
]}

机构：

[1] Harbin Med Univ, Coll Pharm, Dept Med Chem & Nat Med Chem, Harbin, Peoples R China

[2] Harbin Med Univ, Coll Pharm, Key Lab Gut Microbiota & Pharmacogen Heilongjiang, Harbin, Peoples R China

[3] Heilongjiang Univ Tradit Chinese Med, Affiliated Hosp 3, Harbin, Peoples R China

来源：

FRONTIERS IN MICROBIOLOGY | 2023年 / 14卷

关键词：

cyclodepsipeptide; fungi; bacteria; antimicrobial; biological activity; VITRO ANTITRYPANOSOMAL ACTIVITY; ALPHA-PYRONE DERIVATIVES; ACID-CONTAINING PEPTIDES; CYCLIC DEPSIPEPTIDES; ANTIMALARIAL CYCLODEPSIPEPTIDE; SECONDARY METABOLITES; FUNGUS; ANTIFUNGAL; DISCOVERY; NANNOCYSTIN;

D O I：

10.3389/fmicb.2023.1276928

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Cyclodepsipeptides are a large family of peptide-related natural products consisting of hydroxy and amino acids linked by amide and ester bonds. A number of cyclodepsipeptides have been isolated and characterized from fungi and bacteria. Most of them showed antitumor, antifungal, antiviral, antimalarial, and antitrypanosomal properties. Herein, this review summarizes the recent literatures (2010-2022) on the progress of cyclodepsipeptides from fungi and bacteria except for those of marine origin, in order to enrich our knowledge about their structural features and biological sources.

引用

页数：14

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