CryoREAD provides fully automated DNA-RNA structure modeling for cryo-EM maps

CryoREAD automatically builds DNA-RNA atomic structure from cryo-EM maps. Backbone accuracy is typically >85% and the method is applicable for maps with RNA-only, DNA-only and DNA-RNA-protein complex structures. CryoREAD uses deep learning to identify structure information and subsequently construct the 3D structure of nucleic acids.