Multiple function of lncRNA MALAT1 in cancer occurrence and progression

被引:27
|
作者
Malakoti, Faezeh [1 ,2 ,3 ]
Targhazeh, Niloufar [1 ,2 ]
Karimzadeh, Haniye [4 ,5 ]
Mohammadi, Erfan [6 ,7 ]
Asadi, Milad [7 ]
Asemi, Zatollah [8 ]
Alemi, Forough [1 ,2 ]
机构
[1] Tabriz Univ Med Sci, Fac Med, Dept Biochem, Tabriz, Iran
[2] Tabriz Univ Med Sci, Fac Med, Clin Labs, Tabriz, Iran
[3] Tabriz Univ Med Sci, Students Res Comm, Tabriz, Iran
[4] Isfahan Univ Med Sci, Sch Pharm, Dept Clin Biochem, Esfahan, Iran
[5] Isfahan Univ Med Sci, Isfahan Pharmaceut Sci Res Ctr, Esfahan, Iran
[6] Univ Tabriz, Fac Nat Sci, Dept Biol, Tabriz, Iran
[7] Ege Univ, Hlth Inst, Dept Basic Oncol, Izmir, Turkey
[8] Kashan Univ Med Sci, Res Ctr Biochem & Nutr Metab Dis, Kashan, Iran
关键词
BC; COC; HCC; Lung cancer; MALAT1; miRNAs; OC; OS; LONG NONCODING RNA; HUMAN HEPATOCELLULAR-CARCINOMA; EPITHELIAL OVARIAN-CANCER; BREAST-CANCER; CELL-PROLIFERATION; CISPLATIN-RESISTANCE; SIGNALING PATHWAY; DOWN-REGULATION; REGULATES PROLIFERATION; MESENCHYMAL TRANSITION;
D O I
10.1111/cbdd.14006
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Long non-coding RNAs (lncRNAs) have received particular attention in the last decade due to its engaging in carcinogenesis and tumorigenesis. Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a lncRNA that plays physiological and pathological roles in many aspects of genome function as well as biological processes involved in cell development, differentiation, proliferation, invasion, and migration. In this article, we will review the effects of lncRNA MALAT1 on the progression of six prevalent human cancers by focusing on MALAT1 ability to regulate post-transcriptional modification and signaling pathways.
引用
收藏
页码:1113 / 1137
页数:25
相关论文
共 50 条
  • [21] LncRNA MALAT1 and Ischemic Stroke: Pathogenesis and Opportunities
    Khoshnam, Seyed Esmaeil
    Moalemnia, Arash
    Anbiyaee, Omid
    Farzaneh, Maryam
    Ghaderi, Shahab
    MOLECULAR NEUROBIOLOGY, 2023, 61 (7) : 4369 - 4380
  • [22] LncRNA MALAT1 as a potential therapeutic target in triple negative breast cancer
    Adewunmi, Oluwatoyosi
    Rosen, Jeffrey
    CANCER RESEARCH, 2022, 82 (12)
  • [23] LncRNA MALAT1 promotes relapse of breast cancer patients with postoperative fever
    Li, Zhihua
    Xu, Liang
    Liu, Yong
    Fu, Shaokun
    Tu, Jianhong
    Hu, Yangyang
    Xiong, Qiuyun
    AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2018, 10 (10): : 3186 - 3197
  • [24] Bridging autoimmunity and epigenetics: The influence of lncRNA MALAT1
    Mohan, Syam
    Hakami, Mohammed Ageeli
    Dailah, Hamad Ghaleb
    Khalid, Asaad
    Najmi, Asim
    Zoghebi, Khalid
    Halawi, Maryam A.
    PATHOLOGY RESEARCH AND PRACTICE, 2024, 254
  • [25] METTL16 Inhibits the Malignant Progression of Epithelial Ovarian Cancer through the lncRNA MALAT1/β-Catenin Axis
    Li, Changshu
    Liu, Ji
    Lyu, Yuanyuan
    Ling, Shizhang
    Luo, Yonghong
    ANALYTICAL CELLULAR PATHOLOGY, 2023, 2023
  • [26] Beyond the Genome: Deciphering the Role of MALAT1 in Breast Cancer Progression
    Hussain, Md Sadique
    Agrawal, Mohit
    Shaikh, Nusrat K.
    Saraswat, Nikita
    Bahl, Gurusha
    Maqbool, Mudasir
    Khurana, Navneet
    Bisht, Ajay Singh
    Tufail, Muhammad
    Kumar, Rajesh
    CURRENT GENOMICS, 2024, 25 (05) : 343 - 357
  • [27] Silencing of lncRNA MALAT1 inhibits cell cycle progression via androgen receptor signaling in prostate cancer cells
    Dai, Xiaofan
    Liu, Lingyun
    Liang, Zuowen
    Guo, Kaimin
    Xu, Shengqi
    Wang, Hongliang
    PATHOLOGY RESEARCH AND PRACTICE, 2019, 215 (04) : 712 - 721
  • [28] MALAT1 — a paradigm for long noncoding RNA function in cancer
    Tony Gutschner
    Monika Hämmerle
    Sven Diederichs
    Journal of Molecular Medicine, 2013, 91 : 791 - 801
  • [29] LncRNA MALAT1 facilitated the progression of myocardial infarction by sponging miR-26b
    Huang, Shi-Feng
    Ye, Wen-Chu
    INTERNATIONAL JOURNAL OF CARDIOLOGY, 2021, 335 : 24 - 24
  • [30] Effects of lncRNA MALAT1 and lncRNA NKILA on proliferation, invasion and apoptosis of retinoblastoma
    Gao, Y-X
    Gao, H-X
    Xu, X-Y
    Ding, F-K
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2020, 24 (16) : 8296 - 8307