Bilateral Median Nerve and Brachial Artery Variations in the Arm: A Case Report

During clinical practice, it is essential for physicians to have a sound knowledge of vascular and nerve variations. Patients who present with various clinical signs and symptoms need to be thoroughly investigated with anatomic variations in mind to prevent misdiagnosis. Most nerve variations are related to their formation or their course and are frequently associated with variability of structures that surround them. These structures most commonly include blood vessels, ligaments, and muscles. Such variations should be foremost in a physician's mind when analyzing clinical symptoms. This will aid in accurate diagnosis, and if surgical intervention is warranted, such awareness would minimize intraoperative errors. In this case study, the striking absence of median nerve and brachial artery within the cubital fossa bilaterally led to the discovery of pronator teres originating from the distal third of the humerus, associated with the bifurcation of the brachial artery at the middle third of the humerus into the ulnar and radial arteries. The median nerve ran beneath the pronator teres along with the ulnar artery and was thereby absent at the cubital fossa. Such variations observed bilaterally have not yet been reported in the literature. Knowledge of such variations can be very profound as this region involves surgical significance for several conditions, such as creation of arteriovenous fistulas (AVFs) for hemodialysis, treatment of supracondylar and radial head fractures, and cubital tunnel syndrome.