Divergent Synthesis of Trifluoromethyl-Substituted 1,2-Dihydroquinoxalines and Diimines by Cascade Reactions of CF3-Imidoyl Sulfoxonium Ylides with Azo Compounds

被引：12

作者：

Wei, Guangming ^{[1
]}

Zheng, Dongling ^{[1
]}

Li, Chen ^{[1
]}

Chen, Zhengkai ^{[1
]}

Wu, Xiao-Feng ^{[2
,3
]}

机构：

[1] Zhejiang Sci Tech Univ, Dept Chem, Key Lab Surface & Interface Sci Polymer Mat Zheji, Hangzhou 310018, Peoples R China

[2] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian Natl Lab Clean Energy, Dalian 116023, Liaoning, Peoples R China

[3] Leibniz Inst Katalyse eV, D-18059 Rostock, Germany

来源：

ORGANIC LETTERS | 2023年 / 25卷 / 38期

关键词：

ANNULATION; CYCLOADDITION; HYDROGENATION; DERIVATIVES; INHIBITORS; IMINES; ACCESS; ROUTE;

D O I：

10.1021/acs.orglett.3c02718

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A base-mediated cascade reaction of CF3-imidoyl sulfoxonium ylides and azo compounds has been achieved, allowing for facile access to trifluoromethyl-substituted 1,2-dihydroquinoxalines and diimines in moderate to excellent yields. Noteworthy is that the unusual N-N bond cleavage and rearrangement of azo compounds are involved in the transformations.

引用

页码：7046 / 7050

页数：5