Efficacy and safety of lebrikizumab is maintained to two years in patients with moderate-to-severe atopic dermatitis

被引:0
|
作者
Guttman-Yassky, Emma [1 ]
Weidinger, Stephan [2 ]
Simpson, Eric [3 ]
Gooderham, Melinda [4 ,5 ]
Irvine, Alan [6 ]
Spelman, Lynda [7 ,8 ]
Silverberg, Jonathan [9 ]
Elmaraghy, Hany [10 ]
DeLuca-Carter, Louise [10 ]
Piruzeli, Maria Lucia Buziqui [10 ]
Hu, Chaoran [10 ]
Yang, Fan Emily [10 ]
Pierce, Evangeline [10 ]
Bardolet, Laia [11 ]
Thaci, Diamant [12 ]
机构
[1] Icahn Sch Med Mt Sinai, New York, NY 10029 USA
[2] Univ Hosp Schleswig Holstein, Kiel, Germany
[3] Oregon Hlth & Sci Univ, Portland, OR 97201 USA
[4] Prob Med Res, SKiN Dermatol, Peterborough, ON, Canada
[5] Queens Univ, Peterborough, ON, Canada
[6] Childrens Hlth Ireland, Dublin, Ireland
[7] Verac Clin Res, Woolloongabba, Qld, Australia
[8] Prob Med Res, Woolloongabba, Qld, Australia
[9] George Washington Univ, Sch Med & Hlth Sci, Washington, DC 20052 USA
[10] Eli Lilly & Co, Indianapolis, IN 46285 USA
[11] Almirall SA, Barcelona, Spain
[12] Univ Lubeck, Inst & Comprehens Ctr Inflammatory Med, Lubeck, Germany
关键词
atopic dermatitis; efficacy; lebrikizumab; phase; 3; trials; safety;
D O I
10.1093/bjd/ljad498.005
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
494
引用
收藏
页码:II3 / II4
页数:2
相关论文
共 50 条
  • [31] Conjunctivitis does not increase with longer duration of lebrikizumab exposure in patients with moderate-to-severe atopic dermatitis
    Armstrong, April
    Wollenberg, Andreas
    de Bruin-Weller, Marjolein
    Lio, Peter
    Natalie, Chitra R.
    Zhao, Fangyi
    Atwater, Amber Reck
    Jimenez, Gemma
    Chu, Chia-Yu
    Vestergaard, Christian
    BRITISH JOURNAL OF DERMATOLOGY, 2024, 190 : II5 - II6
  • [32] Safety of Lebrikizumab in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis: An Integrated Analysis of Eight Clinical Trials
    Gold, Linda Stein
    Thaci, Diamant
    Thyssen, Jacob P.
    Gooderham, Melinda
    Laquer, Vivian
    Moore, Angela
    Natalie, Chitra R.
    Zhao, Fangyi
    Meskimen, Eric
    Elmaraghy, Hany
    Montmayeur, Sonia
    Gallo, Gaia
    Jimenez, Gemma
    de Bruin-Weller, Marjolein
    AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2023, 24 (04) : 595 - 607
  • [33] Safety and Efficacy of Lebrikizumab in Adolescent Patients with Moderate-to-Severe Atopic Dermatitis: A 52-Week, Open-Label, Phase 3 Study
    Paller, Amy S.
    Flohr, Carsten
    Eichenfield, Lawrence F. F.
    Irvine, Alan D. D.
    Weisman, Jamie
    Soung, Jennifer
    Correia, Ana Pinto
    Natalie, Chitra R. R.
    Capriles, Claudia Rodriguez
    Pierce, Evangeline
    Reifeis, Sarah
    Lima, Renata Gontijo
    Tubau, Clara Armengol
    Laquer, Vivian
    Weidinger, Stephan
    DERMATOLOGY AND THERAPY, 2023, 13 (07) : 1517 - 1534
  • [34] Safety and Efficacy of Lebrikizumab in Adolescent Patients with Moderate-to-Severe Atopic Dermatitis: A 52-Week, Open-Label, Phase 3 Study
    Amy S. Paller
    Carsten Flohr
    Lawrence F. Eichenfield
    Alan D. Irvine
    Jamie Weisman
    Jennifer Soung
    Ana Pinto Correia
    Chitra R. Natalie
    Claudia Rodriguez Capriles
    Evangeline Pierce
    Sarah Reifeis
    Renata Gontijo Lima
    Clara Armengol Tubau
    Vivian Laquer
    Stephan Weidinger
    Dermatology and Therapy, 2023, 13 (7) : 1517 - 1534
  • [35] Efficacy and Safety of Lebrikizumab in Combination With Topical Corticosteroids in Adolescents and Adults With Moderate-to-Severe Atopic Dermatitis A Randomized Clinical Trial (ADhere)
    Simpson, Eric L. L.
    Gooderham, Melinda
    Wollenberg, Andreas
    Weidinger, Stephan
    Armstrong, April
    Soung, Jennifer
    Ferrucci, Silvia
    Lima, Renata Gontijo
    Witte, Michael M. M.
    Xu, Wen
    ElMaraghy, Hany
    Natalie, Chitra R. R.
    Pierce, Evangeline
    Blauvelt, Andrew
    ADhere Investigators
    JAMA DERMATOLOGY, 2023, 159 (02) : 182 - 191
  • [36] Safety of Lebrikizumab in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis: An Integrated Analysis of Eight Clinical Trials
    Linda Stein Gold
    Diamant Thaçi
    Jacob P. Thyssen
    Melinda Gooderham
    Vivian Laquer
    Angela Moore
    Chitra R. Natalie
    Fangyi Zhao
    Eric Meskimen
    Hany Elmaraghy
    Sonia Montmayeur
    Gaia Gallo
    Gemma Jimenez
    Marjolein de Bruin-Weller
    American Journal of Clinical Dermatology, 2023, 24 : 595 - 607
  • [37] Lebrikizumab demonstrates significant efficacy versus placebo across racial and ethnic subgroups in patients with moderate-to-severe atopic dermatitis
    Alexis, Andrew
    Ardern-Jones, Michael
    Chovatiya, Raj
    Flohr, Carsten
    Irvine, Alan
    AlMurrawi, Muna
    Atwater, Amber Reck
    Ding, Yuxin
    Qiao, Meihua
    Pierce, Evangeline
    Pau-Charles, Ignasi
    Heath, Candrice
    BRITISH JOURNAL OF DERMATOLOGY, 2024, 190 : II20 - II21
  • [38] Efficacy of lebrikizumab in adults and adolescents with moderate-to-severe atopic dermatitis by age of onset: analysis of two phase 3 clinical trials
    Zirwas, Matthew J.
    Boguniewicz, Mark
    Rosmarin, David
    Fuxench, Zelma Chiesa
    Warren, Richard B.
    Torres, Tiago
    de Bruin-Weller, Marjolein
    Dawson, Zach
    Atwater, Amber Reck
    Elmaraghy, Hany
    Pierce, Evangeline
    Bardolet, Laia
    Zhong, Jinglin
    Armstrong, April W.
    BRITISH JOURNAL OF DERMATOLOGY, 2024, 191 : 54 - 56
  • [39] EFFICACY AND SAFETY OF DUPILUMAB IN CHILDREN AGED 6 MONTHS TO 5 YEARS WITH MODERATE-TO-SEVERE ATOPIC DERMATITIS
    Worrell, Richard
    Paller, Amy S.
    Siegfried, Elaine C.
    Simpson, Eric L.
    Wollenberg, Andreas
    Gonzalez, Mercedes E.
    Sidbury, Robert
    Lockshin, Benjamin
    Dubost-Brama, Ariane
    Bansal, Ashish
    INTERNAL MEDICINE JOURNAL, 2022, 52 : 31 - 32
  • [40] Dupilumab Efficacy and Safety in Adolescents with Moderate-to-Severe Atopic Dermatitis: A Case Series
    Mareschal, Adrien
    Puzenat, Eve
    Aubin, Francois
    ACTA DERMATO-VENEREOLOGICA, 2020, 100 (01)