Dose and secondary cancer-risk estimation of patients undergoing high dose rate intracavitary gynaecological brachytherapy

被引:1
|
作者
Doudoo, Chris Osam [1 ,2 ]
Gyekye, Prince Kwabena [2 ]
Emi-Reynolds, Geoffrey [2 ]
Adu, Simon [2 ]
Kpeglo, David Okoh [2 ]
Tagoe, Samuel Nii Adu [3 ]
Agyiri, Kofi [3 ]
机构
[1] Sweden Ghana Med Ctr, POB MD 1879, Accra, Ghana
[2] Univ Ghana, Sch Nucl & Allied Sci, POB AE 1, Accra, Ghana
[3] Natl Ctr Radiotherapy & Nucl Med, Korle Bu, Accra, Ghana
关键词
ALARA; Dose optimisation; Electronic dosimeters; Organ doses; Radiotherapy; RADIATION-INDUCED CANCER; BODY-MASS INDEX; 2ND CANCERS; RADIOTHERAPY; SURVIVORS; PROSTATE; THERAPY; ORGANS;
D O I
10.1016/j.jmir.2023.03.031
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Dose and secondary cancer risk of the breast and thyroid during high dose rate (HDR) brachytherapy for 100 gynaecological cancer patients have been estimated. The organ doses were measured using LiF thermoluminescence dosimeters LiF (TLD-100). Patient demographic data (i.e. age and body mass index (BMI)) were also collected observed for the correlation between age and breast dose; body mass index (BMI) and breast dose as well as BMI and thyroid dose. The average breast dose for cervical, vaginal and endometrial cancers were 7.44, 8.03 and 10.72 mGy, respectively. The average thyroid dose for cervical, vaginal and endometrial cancers were 2.32, 2.95 and 3.02 mGy, respectively. Excess absolute risk of the breast increased with atat exposure. It is recommended to intensify post-treatment follow-ups and optimize the doses to the breast and thyroid.
引用
收藏
页码:335 / 342
页数:8
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