The 17th EFMC Short Course on Medicinal Chemistry on Small Molecule Protein Degraders

被引：3
|
作者：
Ciulli, Alessio [1 ]
O'Connor, Suzanne [1 ]
Chung, Chun-Wa [2 ]
Hartung, Ingo V. [3 ]
Testa, Andrea [4 ]
Daniels, Danette L. [5 ]
Heitman, Laura H. [6 ]
机构：
[1] Univ Dundee, Ctr Targeted Prot Degradat, Sch Life Sci, 1 James Lindsay Pl, Dundee DD1 5JJ, Scotland
[2] GlaxoSmithKline Res & Dev Ltd, Gunnelswood Rd, Stevenage SG5 4HT, England
[3] Merck Healthcare KGaA, Frankfurter Str 250, D-64293 Darmstadt, Germany
[4] Amphista Therapeut Ltd, Cori Bldg,Granta Pk, Cambridge CB21 6GQ, England
[5] Foghorn Therapeut, 500 Technol Sq, Cambridge, MA 02139 USA
[6] Leiden Acad Ctr Drug Res LACDR, Oncode Inst, Div Drug Discovery & Safety, POB 9502, NL-2300RA Leiden, Netherlands
来源：
CHEMMEDCHEM | 2023年 / 18卷 / 20期
关键词：
medicinal chemistry; molecular glues; PROTACs; protein degraders; drug design; STRUCTURAL BASIS; DEGRADATION; PROTACS;
D O I：
10.1002/cmdc.202300464
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The 17th EFMC Short Course on Medicinal Chemistry took place April 23-26, 2023 in Oegstgeest, near Leiden in the Netherlands. It covered for the first time the exciting topic of Targeted Protein Degradation (full title: Small Molecule Protein Degraders: A New Opportunity for Drug Design and Development). The course was oversubscribed, with 35 attendees and 6 instructors mainly from Europe but also from the US and South Africa, and representing both industry and academia. This report summarizes the successful event, key lectures given and topics discussed.
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页数：7
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