Efficient Synthesis of 2-Ethylhexanoic Acid via N-Hydroxyphthalimide Catalyzed Oxidation of 2-Ethylhexanal with Oxygen

被引：2

作者：

Czieszowic, Lukasz ^{[1
,2
,3
]}

Orlinska, Beata ^{[2
,3
]}

Lisicki, Dawid ^{[2
,3
]}

Pankalla, Ewa ^{[1
]}

机构：

[1] Grp Azoty Zaklady Azotowe Kedzierzyn SA, Mostowa 30A, PL-47220 Kedzierzyn Kozle, Poland

[2] Silesian Tech Univ, Dept Chem Organ Technol & Petrochem, Akad 2A, PL-44100 Gliwice, Poland

[3] Silesian Tech Univ, PhD Sch, Akad 2A, PL-44100 Gliwice, Poland

来源：

MATERIALS | 2023年 / 16卷 / 17期

关键词：

oxidation; 2-ethylhexanoic acid; N-hydroxyphthalimide; aldehyde; AEROBIC OXIDATION; LIQUID-PHASE; ALDEHYDES; SELECTIVITY; SOLVENT;

D O I：

10.3390/ma16175778

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

An efficient method for the synthesis of 2-ethylhexanoic acid has been reported. The method involves the 2-ethylhexanal oxidation using oxygen or air in the presence of N-hydroxyphthalimide in isobutanol as a solvent under mild conditions. A high selectivity of >99% for 2-ethylhexanoic acid was achieved. The influence of catalyst amount, solvent type and quantity, temperature, and reaction time on the product composition was studied. The developed method is in line with the global trends aimed at developing green oxidation processes as well as having potential for implementation in industry due to its high selectivity, cost-effective oxidizing agent, and mild reaction conditions. The use of isobutanol as a solvent is of crucial importance providing an opportunity for potential producers of 2-EHAL from butanal to employ the less valuable alcohol.

引用

页数：10

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