EPIGENETIC REGULATORS TET2 AND POLYCOMB REPRESSIVE COMPLEX 2 (PRC2) COORDINATE GENE EXPRESSION IN MYELODYSPLASTIC SYNDROME (MDS)

被引：0
|
作者：
Myers, Jacquelyn [1 ,2 ]
Henriet, Elodie [1 ]
Wallace, LaShanale [1 ]
Metidji, Amina [1 ]
Skorupa, Jordan [1 ]
Leal-Cervantes, Ana [1 ]
Pruett-Miller, Shondra [3 ,4 ]
Fan, Yiping [5 ]
Iacobucci, Ilaria [6 ]
Haferlach, Torsten [7 ]
Mullighan, Charles [6 ]
Obeng, Esther [1 ]
机构：
[1] St Jude Childrens Res Hosp, Div Mol Oncol, Dept Oncol, Memphis, TN USA
[2] St Jude Childrens Res Hosp, Div Mol Oncol, Dept Oncol, Bartlett, IL USA
[3] St Jude Childrens Res Hosp, Dept Cell & Mol Biol, Memphis, TN USA
[4] St Jude Childrens Res Hosp, Ctr Adv Genome Engn, Memphis, TN USA
[5] St Jude Childrens Res Hosp, Ctr Appl Bioinformat, Memphis, TN 38105 USA
[6] St Jude Childrens Res Hosp, Dept Pathol, Memphis, TN USA
[7] MLL Munchner Leukamielabor GmbH, Max Lebsche Pl 31, D-81377 Munich, Germany
来源：
EXPERIMENTAL HEMATOLOGY | 2023年 / 124卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
3138
引用
收藏
页码：S118 / S118
页数：1
相关论文
共 50 条
  • [41] AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2
    Kim, Hana
    Kang, Keunsoo
    Kim, Joomyeong
    NUCLEIC ACIDS RESEARCH, 2009, 37 (09) : 2940 - 2950
  • [42] Polycomb Repressive Complex 2 (PRC2) Emerges as a Key Driver of HLA Class II Negative Post-Transplantation Relapse
    Gambacorta, Valentina
    Gnani, Daniela
    Zito, Laura
    Beretta, Stefano
    Zanotti, Lucia
    Oliveira, Giacomo
    Cittaro, Davide
    Merelli, Ivan
    Ciceri, Fabio
    Di Micco, Raffaella
    Vago, Luca
    BONE MARROW TRANSPLANTATION, 2020, 55 (SUPPL 1) : 26 - 26
  • [43] The domesticated transposase ALP2 mediates formation of a novel Polycomb protein complex by direct interaction with MSI1, a core subunit of Polycomb Repressive Complex 2 (PRC2)
    Velanis, Christos N.
    Perera, Pumi
    Thomson, Bennett
    de Leau, Erica
    Liang, Shih Chieh
    Hartwig, Ben
    Foerderer, Alex
    Thornton, Harry
    Arede, Pedro
    Chen, Jiawen
    Webb, Kimberly M.
    Guemues, Serin
    De Jaeger, Geert
    Page, Clinton A.
    Hancock, C. Nathan
    Spanos, Christos
    Rappsilber, Juri
    Voigt, Philipp
    Turck, Franziska
    Wellmer, Frank
    Goodrich, Justin
    PLOS GENETICS, 2020, 16 (05):
  • [44] Polycomb repressive complex 2 inhibitors: emerging epigenetic modulators
    Danishuddin
    Subbarao, Naidu
    Faheem, Mohammad
    Khan, Shahper Nazeer
    DRUG DISCOVERY TODAY, 2019, 24 (01) : 179 - 188
  • [45] Combinatorial Epigenetic Aberration Propagates in Myelodysplastic Syndrome in the Setting of Concurrent Loss of Tet2 and Ezh2
    Hasegawa, Nagisa
    Sashida, Goro
    Oshima, Motohiko
    Matsui, Hirotaka
    Saraya, Atsunori
    Wang, Changshan
    Muto, Tomoya
    Nakaseko, Chiaki
    Yokote, Koutaro
    Iwama, Atsushi
    BLOOD, 2015, 126 (23)
  • [46] TET2 gene expression and 5-hydroxymethylcytosine levels are decreased in pediatric patients with myelodysplastic syndrome
    Coutinho, D.
    Monte-Mor, B. C. R.
    Vianna, D.
    Rouxinol, S.
    Batalha, A. B.
    Bueno, A. P.
    Pombo-de-Oliveira, M. S.
    Abdelhay, E.
    Zalcberg, I.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : S101 - S102
  • [47] Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells
    Lovorka Stojic
    Zuzana Jasencakova
    Carolina Prezioso
    Alexandra Stützer
    Beatrice Bodega
    Diego Pasini
    Rebecca Klingberg
    Chiara Mozzetta
    Raphael Margueron
    Pier Lorenzo Puri
    Dirk Schwarzer
    Kristian Helin
    Wolfgang Fischle
    Valerio Orlando
    Epigenetics & Chromatin, 4
  • [48] Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells
    Stojic, Lovorka
    Jasencakova, Zuzana
    Prezioso, Carolina
    Stuetzer, Alexandra
    Bodega, Beatrice
    Pasini, Diego
    Klingberg, Rebecca
    Mozzetta, Chiara
    Margueron, Raphael
    Puri, Pier Lorenzo
    Schwarzer, Dirk
    Helin, Kristian
    Fischle, Wolfgang
    Orlando, Valerio
    EPIGENETICS & CHROMATIN, 2011, 4
  • [49] RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2
    Célia Alecki
    Victoria Chiwara
    Lionel A. Sanz
    Daniel Grau
    Osvaldo Arias Pérez
    Elodie L. Boulier
    Karim-Jean Armache
    Frédéric Chédin
    Nicole J. Francis
    Nature Communications, 11
  • [50] Involvement of TET2 in Regulation of Epigenetic Silencing in MDS and Related Myeloid Malignancies
    Szpurka, Hadrian
    Jankowska, Anna M.
    Ng, Kwok Peng
    Clevenger, Joshua R.
    Saunthararajah, Yogen
    Maciejewski, Jaroslaw P.
    BLOOD, 2009, 114 (22) : 1136 - 1136
12345