Composite Angioimmunoblastic T-Cell Lymphoma and Diffuse Large B-Cell Lymphoma Presenting with Distributive Shock

被引:0
|
作者
Hariharan, Nisha [1 ]
Kabadi, Alisha [2 ]
Don, Michelle [3 ]
Odish, Mazen [2 ]
Heyman, Benjamin [4 ]
机构
[1] Univ Calif San Diego, Dept Med, Div Hematol Oncol, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Dept Med, Div Pulm Crit Care Sleep Med & Physiol, La Jolla, CA 92093 USA
[3] Univ Calif San Diego, Dept Pathol, La Jolla, CA 92093 USA
[4] Univ Calif San Diego, Dept Med, Div Regenerat Med, La Jolla, CA 92093 USA
关键词
angioimmunoblastic T-cell lymphoma; diffuse large B-cell lymphoma; composite lymphoma; brentuximab vedotin; shock; HODGKIN-LYMPHOMA; CLASSIFICATION; INSIGHTS; PATIENT;
D O I
10.3390/hematolrep15040064
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diffuse large B-cell lymphoma (DLBCL) and angioimmunoblastic T-cell lymphoma (AITL) are two subtypes of non-Hodgkin lymphoma (NHL). The simultaneous occurrence of DLBCL and AITL in a composite lymphoma is very rare, and there are no established treatment regimens. We present the case of an 85-year-old male admitted to the intensive care unit with distributive shock, lymphocytosis, and lymphadenopathy, who was subsequently diagnosed with composite AITL and DLBCL, and treated with brentuximab vedotin (BV) and rituximab. To our knowledge, this is the first case of composite lymphoma presenting with distributive shock and treated with BV and rituximab, with successful resolution of shock.
引用
收藏
页码:627 / 633
页数:7
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