type iii collagen;
glomerular diseases;
collagen deposition;
hyperglycemia;
renal dysfunction;
renal biopsy;
nephrotic-range proteinuria;
diabetic nephropathy;
collagenofibrotic glomerulopathy;
D O I:
10.7759/cureus.44284
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Collagenofibrotic glomerulopathy (CG) is a poorly understood kidney disease characterized by extensive deposition of abnormal type III collagen within the glomeruli. We report the case of a 25-year-old man with known type I diabetes mellitus who presented to the emergency department with diaphoresis, nephroticrange proteinuria, hypertension, and elevated creatinine. Renal biopsy revealed combined collagenofibrotic glomerulopathy and diabetic nephropathy. This case highlights the clinicopathological features of type III collagen glomerulopathy and its possible association with diabetic nephropathy.