A mechanistic blueprint for enzymatic reduction by a modular polyketide synthase

被引：0
|
作者：
Fraley, Amy E. [1 ]
机构：
[1] Eidgenoss TH ETH Zurich, Inst Microbiol, Zurich, Switzerland
来源：
STRUCTURE | 2023年 / 31卷 / 09期
关键词：
D O I：
10.1016/j.str.2023.08.009
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this issue of Structure, McCullough et al. describe linker peptides that serve as a "hydrophobic glue"to arrange the domains within the reducing region of a modular polyketide synthase. Comparisons to structural data from other megasynthases identified features that are unique to modular systems.
引用
收藏
页码：1013 / 1015
页数：3
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