Visible-Light-Induced, Catalyst-Free Monofluoromethyl Sulfonylation of Alkenes with Iodine(III) Reagent and DABSO

被引：7

作者：

Ye, Zhi-Peng ^{[1
]}

Yang, Jing-Song ^{[1
]}

Yang, Si-Jia ^{[1
]}

Guo, Meng ^{[1
]}

Yuan, Chu-Ping ^{[1
]}

Ye, Yong-Qing ^{[1
]}

Chen, Hong-Bin ^{[1
,2
]}

Xiang, Hao-Yue ^{[1
]}

Chen, Kai ^{[1
]}

Yang, Hua ^{[1
]}

机构：

[1] Cent South Univ, Coll Chem & Chem Engn, Changsha 410083, Peoples R China

[2] Jiangxi Time Chem Co Ltd, Fuzhou 344800, Peoples R China

来源：

ORGANIC LETTERS | 2023年 / 25卷 / 38期

基金：

中国国家自然科学基金;

关键词：

SULFUR-DIOXIDE; SULFOXIDES; FLUORINE; SULFONES; ACCESS;

D O I：

10.1021/acs.orglett.3c02766

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A visible-light-induced radical relay strategy to access heterocycles bearing a monofluoromethylsufonyl moiety is reported, with PhI(OCOCH2F)(2) as the CH2F radical precursor and DABSO as the SO2 source. A range of oxindoles, containing a CH2FSO2CH2- group at the C3 position, were synthesized from N-arylacrylamides in up to 97% yields. The protocol features catalyst-free photochemical tandem, mild reaction conditions, broad functional group compatibility, and good to excellent yields.

引用

页码：7062 / 7066

页数：5

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