The Impact of Metabolic Syndrome Components on Erectile Function in Patients with Type 2 Diabetes

被引:4
|
作者
Katsimardou, Alexandra [1 ]
Patoulias, Dimitrios [1 ]
Zografou, Ioanna [1 ]
Siskos, Fotios [1 ]
Stavropoulos, Konstantinos [1 ]
Imprialos, Konstantinos [1 ]
Tegou, Zoi [1 ]
Boulmpou, Aristi [2 ]
Georgopoulou, Vivian [1 ]
Hatzipapa, Nikoleta [1 ]
Papadopoulos, Christodoulos [2 ]
Doumas, Michael [1 ,3 ]
机构
[1] Aristotle Univ Thessaloniki, Hippokrat Gen Hosp, Propedeut Dept Internal Med 2, Thessaloniki 54642, Greece
[2] Aristotle Univ Thessaloniki, Hippokrat Gen Hosp, Dept Cardiol 3, Thessaloniki 54642, Greece
[3] George Washington Univ, Vet Affairs Med Ctr, Washington, DC 20422 USA
关键词
erectile dysfunction; sexual dysfunction; type 2 diabetes mellitus; metabolic syndrome; hypertension; obesity; triglycerides; HDL; CARDIOVASCULAR-DISEASE; INTERNATIONAL INDEX; ENDOTHELIAL-CELLS; DYSFUNCTION; RISK; PREVALENCE; MEN; EPIDEMIOLOGY; HDL;
D O I
10.3390/metabo13050617
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Erectile dysfunction is commonly encountered in diabetic patients and in patients with metabolic syndrome; however, only a few studies have assessed patients with metabolic syndrome and type 2 diabetes mellitus (T2DM) regarding their sexual function. The purpose of this study is to examine the effect of metabolic syndrome and its components on the erectile function of T2DM patients. A cross-sectional study including T2DM patients was conducted from November 2018 until November 2020. Participants were evaluated for the presence of metabolic syndrome and their sexual function was assessed using the International Index of Erectile Function (IIEF) questionnaire. A total of 45 consecutive male patients participated in this study. Metabolic syndrome was diagnosed in 84.4% and erectile dysfunction (ED) in 86.7% of them. Metabolic syndrome was not associated with ED or ED severity. Among metabolic syndrome components, only high-density lipoprotein cholesterol (HDL) was associated with ED [x(2) (1, n = 45) = 3.894, p = 0.048; OR = 5.5 (95% CI: 0.890-33.99)] and with the IIEF erectile function scores (median 23 vs. 18, U = 75, p = 0.012). Multiple regression analyses showed that HDL was non-significantly associated with the IIEF erectile function scores. In conclusion, among T2DM patients HDL is associated with ED.
引用
收藏
页数:10
相关论文
共 50 条
  • [41] Impact of the metabolic syndrome on erectile dysfunction
    Guay A.T.
    Traish A.M.
    Current Sexual Health Reports, 2008, 5 (4) : 163 - 167
  • [42] Klinefelter's syndrome, type 2 diabetes and the metabolic syndrome: the impact of body composition
    Bojesen, Anders
    Host, Christian
    Gravholt, Claus H.
    MOLECULAR HUMAN REPRODUCTION, 2010, 16 (06) : 396 - 401
  • [43] DISTINCT PLASMA FATTY ACIDS ASSOCIATE WITH COMPONENTS OF THE METABOLIC SYNDROME IN HEALTHY OFFSPRING OF TYPE 2 DIABETES PATIENTS
    Scheja, L.
    Vossen, M.
    Toedter, K.
    Beisiegel, U.
    ATHEROSCLEROSIS SUPPLEMENTS, 2010, 11 (02) : 80 - 80
  • [44] Relation of serum magnesium level to microvascular complications and the components of metabolic syndrome in patients with type 2 diabetes mellitus
    Heba M. Yossef
    Nashwa S. Ghanem
    Ula M. Al-Jarhi
    Ollfat G. Shaker
    The Egyptian Journal of Internal Medicine, 2017, 29 (3) : 100 - 104
  • [45] Metabolic syndrome components in Indian migrants with type 2 diabetes - A matched comparative study
    Foucan, L.
    Delounneaux, J.
    Donnet, J. P.
    Bangou, J.
    Larifla, L.
    Messerchmitt, C.
    Salmi, L. R.
    Kangambega, P.
    DIABETES & METABOLISM, 2006, 32 (04) : 337 - 342
  • [46] Prevalence of components of the metabolic syndrome in schoolchildren with newly diagnosed type 2 diabetes mellitus
    Urakami, Tatsuhiko
    Suzuki, Junichi
    Yoshida, Ayako
    Saito, Hiroshi
    Wada, Mika
    Takahashi, Shouri
    Mugishima, Hideo
    PEDIATRIC DIABETES, 2009, 10 (08) : 508 - 512
  • [47] Analysis of Metabolic Syndrome's components by IDF in the female with diabetes mellitus type 2
    Rajewski, Pawel
    Rajewski, Piotr
    Waleskiewicz, Karolina
    Dobosz, Krzysztof
    FAMILY MEDICINE AND PRIMARY CARE REVIEW, 2008, 10 (03): : 624 - 626
  • [48] Neck Circumference is Associated with Metabolic Syndrome Components in Chinese Subjects with Type 2 Diabetes
    He, Yifei
    Chen, Jin
    Cao, Jingzhu
    Hu, Yanyan
    Li, Hui
    Lu, Jin
    DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2022, 15 : 2781 - 2787
  • [49] Intermediate hyperglycemia in metabolic syndrome predict the risk of precocious onset of erectile dysfunction in type 2 diabetes
    Coca, V.
    Porav, D.
    Coca, M. C.
    Hancu, N.
    JOURNAL OF SEXUAL MEDICINE, 2008, 5 : 99 - 99
  • [50] Impact of Fenofibrate on Type 2 Diabetes Patients with Features of the Metabolic Syndrome: Subgroup Analysis From FIELD
    Hermans, Michel P.
    CURRENT CARDIOLOGY REVIEWS, 2010, 6 (02) : 112 - 118