Evaluation of wound healing activity of GelMA/PCLMA fibrous composites in diabetic model rats

被引:3
|
作者
Calland, Francileia Nogueira Albino [1 ]
Brito, Guilherme de Castro [3 ]
de Sousa, Gustavo Fernandes [3 ]
Oliveira, Francilio de Carvalho [2 ]
Marciano, Fernanda Roberta [3 ]
Lobo, Anderson Oliveira [3 ]
机构
[1] Brazil Univ, Biomed Engn Grad Program, BR-08230030 Sao Paulo, Brazil
[2] Ctr Univ UNINOVAFAPI, BR-64073505 Teresina, PI, Brazil
[3] Fed Univ Piaui UFPI, Mat Sci & Engn Grad Program PPGCM, LIMAV Interdisciplinary Lab Adv Mat, BR-64049550 Teresina, PI, Brazil
关键词
Electrospinning; Bandages; Diabetes; Scaffolds;
D O I
10.1016/j.matlet.2023.133893
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
New strategies are necessary to develop bandages to poor wound healing from diabetic patients. Here, we produced different groups of multifunctional bandages using electrospinning and surface functionalization, then we evaluated the skin tissue regeneration using an in vivo diabetes model. The bandages displayed good tissue integration, evidenced by fibroblast adhesion and mature collagen (type I) formation. The group have developed these biomaterials and it have been using for different biomedical applications.
引用
收藏
页数:4
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