Pharmacological inhibiting STAT5 for the treatment of FLT3-ITD-positive acute myeloid leukemia with triciribine phosphate monohydrate

被引：2
|
作者：
Wu, Hong [1 ,2 ]
Ge, Juan [1 ,3 ]
Zou, Fengming [1 ,2 ]
Jiang, Zongru [1 ]
Wang, Beilei [1 ,2 ]
Yuan, Xinyu [1 ,3 ]
Long, Kaili [1 ,3 ]
Liu, Jing [1 ,2 ,3 ,4 ]
Wang, Wenchao [1 ,2 ,3 ,4 ]
Liu, Qingsong [1 ,2 ,3 ,4 ]
机构：
[1] Chinese Acad Sci, Inst Hlth & Med Technol, Hefei Inst Phys Sci, Anhui Prov Key Lab Med Phys & Technol, Hefei, Anhui, Peoples R China
[2] Chinese Acad Sci, Hefei Canc Hosp, Hefei, Anhui, Peoples R China
[3] Univ Sci & Technol China, Hefei, Anhui, Peoples R China
[4] Chinese Acad Sci, Inst Hlth & Med Technol, Hefei Inst Phys Sci, Hefei 230031, Anhui, Peoples R China
来源：
MEDCOMM | 2023年 / 4卷 / 04期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1002/mco2.294
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页数：4
相关论文
共 50 条
  • [41] Targeting chaperon protein HSP70 as a novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia
    Chen Hu
    Fengming Zou
    Aoli Wang
    Weili Miao
    Qianmao Liang
    Ellen L. Weisberg
    Yinsheng Wang
    Jing Liu
    Wenchao Wang
    Qingsong Liu
    Signal Transduction and Targeted Therapy, 6
  • [42] FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation
    Yoshimoto, Goichi
    Miyamoto, Toshihiro
    Jabbarzadeh-Tabrizi, Siamak
    Iino, Tadafumi
    Rocnik, Jennifer L.
    Kikushige, Yoshikane
    Mori, Yasuo
    Shima, Takahiro
    Iwasaki, Hiromi
    Takenaka, Katsuto
    Nagafuji, Koji
    Mizuno, Shin-ichi
    Niiro, Hiroaki
    Gilliland, Gary D.
    Akashi, Koichi
    BLOOD, 2009, 114 (24) : 5034 - 5043
  • [43] FLT3-ITDos and FLT3-ITDon'ts: navigating maintenance therapy in FLT3-ITD-positive acute myeloid leukemia following stem cell transplantation
    Ragon, Brittany Knick
    BONE MARROW TRANSPLANTATION, 2021, 56 (08) : 1774 - 1776
  • [44] FLT3-ITDos and FLT3-ITDon’ts: navigating maintenance therapy in FLT3-ITD-positive acute myeloid leukemia following stem cell transplantation
    Brittany Knick Ragon
    Bone Marrow Transplantation, 2021, 56 : 1774 - 1776
  • [45] Metformin synergistically sensitizes FLT3-ITD-positive acute myeloid leukemia to sorafenib by promoting mTOR-mediated apoptosis and autophagy
    Wang, Fangfang
    Liu, Zuofeng
    Zeng, Jisha
    Zhu, Hongyan
    Li, Jingjing
    Cheng, Xiaomin
    Jiang, Tao
    Zhang, Li
    Zhang, Chuanfen
    Chen, Tie
    Liu, Ting
    Jia, Yongqian
    LEUKEMIA RESEARCH, 2015, 39 (12) : 1421 - 1427
  • [46] PROPHYLACTIC USE OF SORAFENIB IN PATIENTS WITH FLT3-ITD-POSITIVE ACUTE MYELOID LEUKEMIA UNDERGOING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION
    Liu, Q.
    Xuan, L.
    Fan, Z.
    Jiang, Q.
    Dai, M.
    Shi, P.
    Yin, C.
    Sun, J.
    HAEMATOLOGICA, 2015, 100 : 383 - 383
  • [47] Activation mechanisms of STAT5 by oneogenic Flt3-ITD.
    Choudhary, Chunaram
    Brandts, Christian
    Schwable, Joachim
    Tickenbrock, Lara
    Sargin, Bulent
    Ueker, Andrea
    Bohmer, Frank D.
    Berdel, Wolfgang E.
    Mueller-Tidow, Carsten
    Serve, Hubert
    BLOOD, 2006, 108 (11) : 416A - 416A
  • [48] Activation mechanisms of STAT5 by oncogenic Flt3-ITD
    Choudhary, Chunaram
    Brandts, Christian
    Schwable, Joachim
    Tickenbrock, Lara
    Sargin, Buelent
    Ueker, Andrea
    Boehmer, Frank-D.
    Berdel, Wolfgang E.
    Mueller-Tidow, Carsten
    Serve, Hubert
    BLOOD, 2007, 110 (01) : 370 - 374
  • [49] Prophylactic Use of Sorafenib in Patients with FLT3-ITD-Positive Acute Myeloid Leukemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
    Liu, Qifa
    Xuan, Li
    Fan, Zhiping
    Jiang, Qianli
    Dai, Min
    Shi, Pengcheng
    Yin, Changxin
    Sun, Jing
    BLOOD, 2014, 124 (21)
  • [50] Hidden FLT3-D835Y clone in FLT3-ITD-positive acute myeloid leukemia that evolved into very late relapse with T-lymphoblastic leukemia
    Katagiri, Seiichiro
    Umezu, Tomohiro
    Azuma, Kenko
    Asano, Michiyo
    Akahane, Daigo
    Makishima, Hideki
    Yoshida, Kenichi
    Watatani, Yosaku
    Chiba, Kenichi
    Miyano, Satoru
    Ogawa, Seishi
    Ohyashiki, Junko H.
    Ohyashiki, Kazuma
    LEUKEMIA & LYMPHOMA, 2018, 59 (06) : 1490 - 1493
12345