Imaging biomarkers in the idiopathic inflammatory myopathies

被引:15
|
作者
Zubair, Adeel S. [1 ]
Salam, Sharfaraz [2 ]
Dimachkie, Mazen M. [3 ]
Machado, Pedro M. [2 ,4 ]
Roy, Bhaskar [1 ]
机构
[1] Yale Univ, Dept Neurol, Div Neuromuscular Dis, Sch Med, New Haven, CT 06510 USA
[2] UCL, UCL Queen Sq Inst Neurol, Dept Neuromuscular Dis, London, England
[3] Univ Kansas, Dept Neurol, Med Ctr, Kansas City, KS USA
[4] UCL, Ctr Rheumatol, Div Med, London, England
来源
FRONTIERS IN NEUROLOGY | 2023年 / 14卷
关键词
myositis-diagnosis; imaging; MRI; inclusion body myositis (IBM); electrical impedance myography; muscle ultrasound; INCLUSION-BODY MYOSITIS; ELECTRICAL-IMPEDANCE MYOGRAPHY; P-31-MAGNETIC RESONANCE SPECTROSCOPY; QUANTITATIVE MUSCLE ULTRASOUND; SPINAL MUSCULAR-ATROPHY; SKELETAL-MUSCLE; JUVENILE DERMATOMYOSITIS; DIAGNOSTIC-VALUE; CLINICAL CHARACTERISTICS; NEUROMUSCULAR DISEASE;
D O I
10.3389/fneur.2023.1146015
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Idiopathic inflammatory myopathies (IIMs) are a group of acquired muscle diseases with muscle inflammation, weakness, and other extra-muscular manifestations. IIMs can significantly impact the quality of life, and management of IIMs often requires a multi-disciplinary approach. Imaging biomarkers have become an integral part of the management of IIMs. Magnetic resonance imaging (MRI), muscle ultrasound, electrical impedance myography (EIM), and positron emission tomography (PET) are the most widely used imaging technologies in IIMs. They can help make the diagnosis and assess the burden of muscle damage and treatment response. MRI is the most widely used imaging biomarker of IIMs and can assess a large volume of muscle tissue but is limited by availability and cost. Muscle ultrasound and EIM are easy to administer and can even be performed in the clinical setting, but they need further validation. These technologies may complement muscle strength testing and laboratory studies and provide an objective assessment of muscle health in IIMs. Furthermore, this is a rapidly progressing field, and new advances are going to equip care providers with a better objective assessment of IIMS and eventually improve patient management. This review discusses the current state and future direction of imaging biomarkers in IIMs.
引用
收藏
页数:13
相关论文
共 50 条
  • [31] Pathogenesis of idiopathic inflammatory myopathies
    Grundtman C.
    Lundberg I.E.
    Current Rheumatology Reports, 2006, 8 (3) : 188 - 195
  • [32] Resistin in idiopathic inflammatory myopathies
    Filkova, Maria
    Hulejova, Hana
    Kuncova, Klara
    Plestilova, Lenka
    Cerezo, Lucie Andres
    Mann, Herman
    Klein, Martin
    Zamecnik, Josef
    Gay, Steffen
    Vencovsky, Jiri
    Senolt, Ladislav
    ARTHRITIS RESEARCH & THERAPY, 2012, 14 (03)
  • [33] Chemokines in idiopathic inflammatory myopathies
    De Paepe, Boel
    Creus, Kim K.
    De Bleecker, Jan L.
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2008, 13 : 2548 - 2557
  • [34] Mortality in idiopathic inflammatory myopathies
    Lundberg, I. E.
    Forbess, C. J.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2008, 26 (05) : S109 - S114
  • [35] Idiopathic inflammatory myopathies and the lung
    Lega, Jean-Christophe
    Reynaud, Quitterie
    Belot, Alexandre
    Fabien, Nicole
    Durieu, Isabelle
    Cottin, Vincent
    EUROPEAN RESPIRATORY REVIEW, 2015, 24 (136): : 216 - 238
  • [36] Idiopathic inflammatory myopathies—a review
    Jonathan Jones
    Robert Wortmann
    Clinical Rheumatology, 2015, 34 : 839 - 844
  • [37] Juvenile Idiopathic Inflammatory Myopathies
    Huber, Adam M.
    PEDIATRIC CLINICS OF NORTH AMERICA, 2018, 65 (04) : 739 - +
  • [38] Relapses in idiopathic inflammatory myopathies
    Miró, O
    Laguno, M
    Grau, JM
    MUSCLE & NERVE, 1999, 22 (08) : 1159 - 1160
  • [39] Idiopathic inflammatory myopathies - myositis
    Dorph, C
    Lundberg, IE
    BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY, 2002, 16 (05): : 817 - 832
  • [40] Cytokines in idiopathic inflammatory myopathies
    Salomonsson, Stina
    Lundberg, Ingrid E.
    AUTOIMMUNITY, 2006, 39 (03) : 177 - 190