X-linked hypophosphatemia, fibroblast growth factor 23 signaling, and craniosynostosis

被引：0

作者：

Grimbly, Chelsey ^{[1
,2
]}

Graf, Daniel ^{[2
,3
]}

Ward, Leanne M. ^{[4
]}

Alexander, R. Todd ^{[1
,2
]}

机构：

[1] Univ Alberta, Dept Pediat, Edmonton Clin Hlth Acad, Edmonton, AB T6G 2R7, Canada

[2] Univ Alberta, Women & Childrens Hlth Res Inst, Edmonton, AB T6G 2R7, Canada

[3] Univ Alberta, Dept Dent & Dent Hyg, Edmonton, AB T6G 2R7, Canada

[4] Univ Ottawa, Childrens Hosp Eastern Ontario, Fac Med, Div Endocrinol & Metab,Dept Pediat, Ottawa, ON K1H 8L1, Canada

来源：

EXPERIMENTAL BIOLOGY AND MEDICINE | 2023年 / 248卷 / 22期

关键词：

Rickets; phosphate; craniosynostosis; fibroblast growth factor 23; hypophosphatemia; X-linked hypophosphatemia; ALKALINE-PHOSPHATASE; SAGITTAL SYNOSTOSIS; FGF RECEPTOR; RICKETS; BONE; RESISTANT; PHEX; MINERALIZATION; OSTEOPONTIN; GENE;

D O I：

10.1177/15353702231222023

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

This review summarizes the current knowledge of fibroblast growth factor 23 signaling in bone and its role in the disease pathology of X-linked hypophosphatemia. Craniosynostosis is an under-recognized complication of X-linked hypophosphatemia. The clinical implications and potential cellular mechanisms invoked by increased fibroblast growth factor 23 signaling causing craniosynostosis are reviewed. Knowledge gaps are identified and provide direction for future clinical and basic science studies.

引用

页码：2175 / 2182

页数：8

共 50 条

[41] Hypertension in Children with X-linked Hypophosphatemia
Chen, Irene
Molakalapalli, Sreya
Torres, Sasha
Ringrose, Jennifer
Ryabets-Lienhard, Anna
Alexander, Todd
HORMONE RESEARCH IN PAEDIATRICS, 2023, 96 (SUPPL 3): : 49 - 50
[42] Hyperparathyroidism in Patients With X-Linked Hypophosphatemia
Lecoq, Anne-Lise
Chaumet-Riffaud, Philippe
Blanchard, Anne
Dupeux, Margot
Rothenbuhler, Anya
Lambert, Benoit
Durand, Emmanuel
Boros, Erika
Briot, Karine
Silve, Caroline
Francou, Bruno
Piketty, Marie
Chanson, Philippe
Brailly-Tabard, Sylvie
Linglart, Agnes
Kamenicky, Peter
JOURNAL OF BONE AND MINERAL RESEARCH, 2020, 35 (07) : 1263 - 1273
[43] GENETIC CODES OF X-LINKED HYPOPHOSPHATEMIA
Onay, Huseyin
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, 2020, 83 : S17 - S20
[44] Burosumab for Pediatric X-Linked Hypophosphatemia
Erik A. Imel
Current Osteoporosis Reports, 2021, 19 : 271 - 277
[45] RADIOLOGICAL FINDINGS IN X-LINKED HYPOPHOSPHATEMIA
Bugdayci, Onur
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, 2020, 83 : S21 - S25
[46] Fibroblast Growth Factor 23 is Elevated in Tenofovir-Related Hypophosphatemia
Saeedi, Ramesh
Jiang, Shi Yuan
Holmes, Daniel T.
Kendler, David L.
CALCIFIED TISSUE INTERNATIONAL, 2014, 94 (06) : 665 - 668
[47] Fibroblast Growth Factor 23 is Elevated in Tenofovir-Related Hypophosphatemia
Ramesh Saeedi
Shi Yuan Jiang
Daniel T. Holmes
David L. Kendler
Calcified Tissue International, 2014, 94 : 665 - 668
[48] Fibroblast Growth Factor 23-Induced Hypophosphatemia in Acute Leukemia
Reinert, Rachel B.
Bixby, Dale
Koenig, Ronald J.
JOURNAL OF THE ENDOCRINE SOCIETY, 2018, 2 (05): : 437 - 443
[49] Pharmacokinetics (PK) and Pharmacodynamics (PD) Following Four Monthly Doses of a Human Monoclonal Anti-FGF23 (Fibroblast Growth Factor 23) Antibody (KRN23) in Adults with X-Linked Hypophosphatemia (XLH)
Zhang, Xiaoping
Imel, Erik Allen
Ruppe, Mary Denise
Weber, Thomas Joseph
Klausner, Mark
Ito, Takahiro
Vergeire, Maria
Humphrey, Jeffrey
Glorieux, Francis H.
Portale, Anthony A.
Insogna, Karl
Peacock, Munro
Carpenter, Thomas O.
ENDOCRINE REVIEWS, 2014, 35 (03)
[50] Fibroblast Growth Factor 23 and Hypophosphatemia: A Case of Hypophosphatemia along the Rickets-Osteomalacia Spectrum
Georges, George T.
Najera, O.
Sowers, Kurt
Sowers, James R.
CARDIORENAL MEDICINE, 2017, 7 (01) : 60 - 65

← 1 2 3 4 5 →