Characterization of leukemia progression in the Cbfb-MYH11 knockin mice by single cell RNA sequencing

被引：2
|
作者：
Diemer, Jamie L. [1 ]
Yu, Kai [1 ]
Kelly, Michael [2 ,4 ]
Zhen, Tao [1 ]
Anderson, Stacie [3 ]
Lopez, Guadalupe [1 ]
Liu, Paul [1 ]
机构：
[1] NIH, Natl Human Genome Res Inst, Div Intramural Res, Oncogenesis & Dev Sect, Bethesda, MD 20892 USA
[2] NIH, Natl Inst Deafness & Other Commun Disorders, Div Intramural Res, Lab Cochlear Dev, Bethesda, MD 20892 USA
[3] NIH, Natl Human Genome Res Inst, Div Intramural Res, Flow Cytometry Core, Bethesda, MD USA
[4] NIH, Ctr Canc Res, Canc Res Technol Program, Frederick Natl Lab Canc Res,Natioal Canc Inst,Sing, Bethesda, MD USA
来源：
LEUKEMIA | 2023年 / 37卷 / 07期
关键词：
ABNORMAL MYELOID PROGENITORS; FUSION GENE; RUNX1;
D O I：
10.1038/s41375-023-01926-9
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：1549 / 1553
页数：5
相关论文
共 50 条
  • [31] Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11
    Castilla, LH
    Wijmenga, C
    Wang, Q
    Stacy, T
    Speck, NA
    Eckhaus, M
    MarinPadilla, M
    Collins, FS
    WynshawBoris, A
    Liu, PP
    CELL, 1996, 87 (04) : 687 - 696
  • [32] Plag1 and Plagl2 are oncogenes that induce acute myeloid leukemia in cooperation with Cbfb-MYH11
    Landrette, SF
    Kuo, YH
    Hensen, K
    van Doorn-Khosrovani, SBV
    Perrat, PN
    Van de Ven, WJM
    Delwel, R
    Castilla, LH
    BLOOD, 2005, 105 (07) : 2900 - 2907
  • [33] Molecular dissection of a hyper-aggressive CBFB-MYH11/FLT3-ITD-positive acute myeloid leukemia
    Lo Iudice, Gabriele
    De Bellis, Eleonora
    Savi, Arianna
    Guarnera, Luca
    Massacci, Alice
    De Nicola, Francesca
    Goeman, Frauke
    Ottone, Tiziana
    Divona, Mariadomenica
    Pallocca, Matteo
    Fanciulli, Maurizio
    Voso, Maria Teresa
    Ciliberto, Gennaro
    JOURNAL OF TRANSLATIONAL MEDICINE, 2022, 20 (01)
  • [34] Molecular dissection of a hyper-aggressive CBFB-MYH11/FLT3-ITD–positive acute myeloid leukemia
    Gabriele Lo Iudice
    Eleonora De Bellis
    Arianna Savi
    Luca Guarnera
    Alice Massacci
    Francesca De Nicola
    Frauke Goeman
    Tiziana Ottone
    Mariadomenica Divona
    Matteo Pallocca
    Maurizio Fanciulli
    Maria Teresa Voso
    Gennaro Ciliberto
    Journal of Translational Medicine, 20
  • [35] Expression of CBFB-MYH11, the human leukemia inv(16) fusion protein results in apoptosis and altered gene expression.
    Zhang, L
    Johnson, B
    Zhao, S
    Xie, Z
    Andreeff, M
    Claxton, DF
    BLOOD, 1998, 92 (10) : 214A - 214A
  • [36] Age and NRAS Mutation Status are Possible Prognostic Markers in Pediatric Acute Myeloid Leukemia with CBFB-MYH11 Fusion Gene
    Hara, Y.
    Shiba, N.
    Ohki, K.
    Yamato, G.
    Sotomatsu, M.
    Tomizawa, D.
    Taki, T.
    Kinoshita, A.
    Kiyokawa, N.
    Arakawa, H.
    Tawas, A.
    Horibe, K.
    Tagal, T.
    Adachi, S.
    Hayashi, Y.
    PEDIATRIC BLOOD & CANCER, 2018, 65 : S78 - S78
  • [37] Age and NRAS Mutation Status are Possible Prognostic Markers in Pediatric Acute Myeloid Leukemia with CBFB-MYH11 Fusion Gene
    Hara, Y.
    Shiba, N.
    Ohki, K.
    Yamato, G.
    Sotomatsu, M.
    Tomizawa, D.
    Taki, T.
    Kinoshita, A.
    Kiyokawa, N.
    Arakawa, H.
    Tawa, A.
    Horibe, K.
    Taga, T.
    Adachi, S.
    Hayashi, Y.
    PEDIATRIC BLOOD & CANCER, 2018, 65 : S178 - S178
  • [38] A CASE OF ACUTE MYELOID LEUKEMIA WITH CO-EXISTING CBFB-MYH11 AND BCR-ABL1 FUSION GENES
    Imanaka, Yusuke
    Matsumura, Risa
    Mizoguchi, Yoko
    Eto, Shohei
    Shimomura, Maiko
    Karakawa, Shuhei
    Doi, Takehiko
    Kawaguchi, Hiroshi
    Tomizawa, Daisuke
    Okada, Satoshi
    PEDIATRIC BLOOD & CANCER, 2022, 69
  • [39] C-KIT with D816Y/V Mutations Cooperate with CBFB-MYH11 to Accelerate Leukemogenesis in Mice
    Zhao, Ling
    Melenhorst, J. Joseph
    Alemu, Lemlem
    Kirby, Martha
    Anderson, Stacie M.
    Hoogstraten-Miller, Shelley
    Kamikubo, Yasuhiko
    Gilliland, D. Gary
    Liu, Pu Paul
    BLOOD, 2009, 114 (22) : 116 - 116
  • [40] A Case of Acute Myeloid Leukemia With inv(16) (p13.1q22); CBFB-MYH11 Presenting With Faggot Cells
    Kim, Jung-Ah
    Shin, Woo Yong
    Kim, Jieun
    Bang, Hae In
    Yoon, Seug Yun
    Won, Jong-Ho
    Park, Rojin
    ANNALS OF LABORATORY MEDICINE, 2021, 41 (03) : 333 - 335
12345