Building a rheumatology biobank for reliable basic/translational research and precision medicine

被引:1
|
作者
Assirelli, Elisa [1 ]
Naldi, Susanna [1 ]
Brusi, Veronica [1 ]
Ciaffi, Jacopo [1 ]
Lisi, Lucia [1 ]
Mancarella, Luana [1 ]
Pignatti, Federica [1 ]
Pulsatelli, Lia [2 ]
Faldini, Cesare [3 ,4 ]
Ursini, Francesco [1 ,4 ]
Neri, Simona [1 ]
机构
[1] IRCCS Ist Ortoped Rizzoli, Med & Rheumatol Unit, Bologna, Italy
[2] IRCCS Ist Ortoped Rizzoli, Lab Immunorheumatol & Tissue Regenerat, Bologna, Italy
[3] IRCCS Ist Ortoped Rizzoli, Orthoped & Traumatol Dept 1, Bologna, Italy
[4] Univ Bologna, Dept Biomed & Neuromotor Sci DIBINEM, Alma Mater Studiorum, Bologna, Italy
关键词
biobanking and biorepositories; rheumatology; precision medicine; standard operating procedures; quality controls; DISEASE-ACTIVITY; CLASSIFICATION CRITERIA; PSORIATIC-ARTHRITIS; BLOOD; VALIDATION; STORAGE; SERUM; SCORE; SPONDYLOARTHRITIS; BIOANALYSIS;
D O I
10.3389/fmed.2023.1228874
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Research biobanks are non-profit structures that collect, manipulate, store, analyze and distribute systematically organized biological samples and data for research and development purposes. Over the recent years, we have established a biobank, the Rheumatology BioBank (RheumaBank) headed by the Medicine and Rheumatology unit of the IRCCS Istituto Ortopedico Rizzoli (IOR) in Bologna, Italy for the purpose of collecting, processing, storing, and distributing biological samples and associated data obtained from patients suffering from inflammatory joint diseases. RheumaBank is a research biobank, and its main objective is to promote large-scale, high-quality basic, translational, and clinical research studies that can help elucidate pathogenetic mechanisms and improve personalization of treatment choice in patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and other spondyloarthritides (SpA).
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页数:10
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