[1] Univ Eastern Finland, Inst Publ Hlth & Clin Nutr, Dept Med, POB 1627, Kuopio 70211, Finland
[2] Univ Eastern Finland, Inst Clin Med, Dept Med, POB 1627, Kuopio 70211, Finland
[3] Wellbeing Serv Cty Cent Finland, Dept Med, Jyvaskyla, Finland
[4] Univ Leicester, Leicester Gen Hosp, Diabet Res Ctr, Leicester, Leics, England